Wan F - Search Results

1

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.

Chung L, Thiele Orberg E, Geis AL, Chan JL, Fu K, DeStefano Shields CE, Dejea CM, Fathi P, Chen J, Finard BB, Tam AJ, McAllister F, Fan H, Wu X, Ganguly S, Lebid A, Metz P, Van Meerbeke SW, Huso DL, Wick EC, Pardoll DM, Wan F, Wu S, Sears CL, Housseau F. Chung L, et al. Among authors: wan f. Cell Host Microbe. 2018 Feb 14;23(2):203-214.e5. doi: 10.1016/j.chom.2018.01.007. Epub 2018 Feb 1. Cell Host Microbe. 2018. PMID: 29398651 Free PMC article.

2

Identification of an N-terminal truncation of the NF-κB p65 subunit that specifically modulates ribosomal protein S3-dependent NF-κB gene expression.

Wier EM, Neighoff J, Sun X, Fu K, Wan F. Wier EM, et al. Among authors: wan f. J Biol Chem. 2012 Dec 14;287(51):43019-29. doi: 10.1074/jbc.M112.388694. Epub 2012 Oct 31. J Biol Chem. 2012. PMID: 23115242 Free PMC article.

3

Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells.

Fu K, Sun X, Zheng W, Wier EM, Hodgson A, Tran DQ, Richard S, Wan F. Fu K, et al. Among authors: wan f. Nat Commun. 2013;4:1909. doi: 10.1038/ncomms2916. Nat Commun. 2013. PMID: 23715268 Free PMC article.

4

Microbiota organization is a distinct feature of proximal colorectal cancers.

Dejea CM, Wick EC, Hechenbleikner EM, White JR, Mark Welch JL, Rossetti BJ, Peterson SN, Snesrud EC, Borisy GG, Lazarev M, Stein E, Vadivelu J, Roslani AC, Malik AA, Wanyiri JW, Goh KL, Thevambiga I, Fu K, Wan F, Llosa N, Housseau F, Romans K, Wu X, McAllister FM, Wu S, Vogelstein B, Kinzler KW, Pardoll DM, Sears CL. Dejea CM, et al. Among authors: wan f. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18321-6. doi: 10.1073/pnas.1406199111. Epub 2014 Dec 8. Proc Natl Acad Sci U S A. 2014. PMID: 25489084 Free PMC article.

5

Metalloprotease NleC suppresses host NF-κB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction.

Hodgson A, Wier EM, Fu K, Sun X, Yu H, Zheng W, Sham HP, Johnson K, Bailey S, Vallance BA, Wan F. Hodgson A, et al. Among authors: wan f. PLoS Pathog. 2015 Mar 10;11(3):e1004705. doi: 10.1371/journal.ppat.1004705. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25756944 Free PMC article.

6

Caspase-3 cleaved p65 fragment dampens NF-κB-mediated anti-apoptotic transcription by interfering with the p65/RPS3 interaction.

Wier EM, Fu K, Hodgson A, Sun X, Wan F. Wier EM, et al. Among authors: wan f. FEBS Lett. 2015 Nov 30;589(23):3581-7. doi: 10.1016/j.febslet.2015.10.019. Epub 2015 Oct 23. FEBS Lett. 2015. PMID: 26526615 Free PMC article.

7

Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation.

Fu K, Sun X, Wier EM, Hodgson A, Liu Y, Sears CL, Wan F. Fu K, et al. Among authors: wan f. Elife. 2016 Jul 25;5:e15018. doi: 10.7554/eLife.15018. Elife. 2016. PMID: 27458801 Free PMC article.

8

Ultrasound imaging of splenomegaly as a proxy to monitor colon tumor development in Apc(min716/+) mice.

Hodgson A, Wier EM, Fu K, Sun X, Wan F. Hodgson A, et al. Among authors: wan f. Cancer Med. 2016 Sep;5(9):2469-76. doi: 10.1002/cam4.842. Epub 2016 Aug 3. Cancer Med. 2016. PMID: 27485505 Free PMC article.

9

Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation.

Sun X, Fu K, Hodgson A, Wier EM, Wen MG, Kamenyeva O, Xia X, Koo LY, Wan F. Sun X, et al. Among authors: wan f. PLoS Biol. 2016 Sep 16;14(9):e1002543. doi: 10.1371/journal.pbio.1002543. eCollection 2016 Sep. PLoS Biol. 2016. PMID: 27635653 Free PMC article.

10

Sam68/KHDRBS1-dependent NF-κB activation confers radioprotection to the colon epithelium in γ-irradiated mice.

Fu K, Sun X, Wier EM, Hodgson A, Hobbs RP, Wan F. Fu K, et al. Among authors: wan f. Elife. 2016 Dec 20;5:e21957. doi: 10.7554/eLife.21957. Elife. 2016. PMID: 27996939 Free PMC article.

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