Li Y - Search Results

1

A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway.

Gong J, Zheng Y, Wang Y, Sheng W, Li Y, Liu X, Si S, Shao R, Zhen Y. Gong J, et al. Among authors: li y. PLoS One. 2018 Feb 2;13(2):e0191984. doi: 10.1371/journal.pone.0191984. eCollection 2018. PLoS One. 2018. PMID: 29394294 Free PMC article.

2

DBDx-based drug combinations show highly potent therapeutic efficacy against human pancreatic cancer xenografts in athymic mice.

Zheng YB, Zhang MR, Li Y, Liu XJ, Zhen YS. Zheng YB, et al. Among authors: li y. Cancer Biol Ther. 2020 Aug 2;21(8):749-757. doi: 10.1080/15384047.2020.1776580. Epub 2020 Jun 17. Cancer Biol Ther. 2020. PMID: 32644888 Free PMC article.

3

The recombinant defensin/HSA fusion protein that inhibits NF-κb associated with intensive macropinocytosis shows potent efficacy against pancreatic cancer.

Du YB, Wang XF, Liu XJ, Li Y, Miao QF, Jiang M, Sheng WJ, Zhen YS. Du YB, et al. Among authors: li y. Biochem Pharmacol. 2022 Jul;201:115057. doi: 10.1016/j.bcp.2022.115057. Epub 2022 Apr 28. Biochem Pharmacol. 2022. PMID: 35489393

4

A novel enediyne-integrated antibody-drug conjugate shows promising antitumor efficacy against CD30⁺ lymphomas.

Wang R, Li L, Zhang S, Li Y, Wang X, Miao Q, Zhen Y. Wang R, et al. Among authors: li y, li l. Mol Oncol. 2018 Mar;12(3):339-355. doi: 10.1002/1878-0261.12166. Epub 2018 Jan 26. Mol Oncol. 2018. PMID: 29316337 Free PMC article.

5

A Macropinocytosis-Intensifying Albumin Domain-Based scFv Antibody and Its Conjugate Directed against K-Ras Mutant Pancreatic Cancer.

Wang X, Sheng W, Wang Y, Li L, Li Y, Zhang S, Liu X, Chen S, Zhen Y. Wang X, et al. Among authors: li y, li l. Mol Pharm. 2018 Jun 4;15(6):2403-2412. doi: 10.1021/acs.molpharmaceut.8b00234. Epub 2018 May 23. Mol Pharm. 2018. PMID: 29757658

6

EGFR-targeting, β-defensin-tailored fusion protein exhibits high therapeutic efficacy against EGFR-expressed human carcinoma via mitochondria-mediated apoptosis.

Liu WJ, Liu XJ, Xu J, Li L, Li Y, Zhang SH, Wang JL, Miao QF, Zhen YS. Liu WJ, et al. Among authors: li y, li l. Acta Pharmacol Sin. 2018 Nov;39(11):1777-1786. doi: 10.1038/s41401-018-0069-8. Epub 2018 Jul 16. Acta Pharmacol Sin. 2018. PMID: 30013033 Free PMC article.

7

The Recombinant and Reconstituted Novel Albumin-Lidamycin Conjugate Shows Lasting Tumor Imaging and Intensively Enhanced Therapeutic Efficacy.

Li L, Hu L, Zhao CY, Zhang SH, Wang R, Li Y, Shao RG, Zhen YS. Li L, et al. Among authors: li y. Bioconjug Chem. 2018 Sep 19;29(9):3104-3112. doi: 10.1021/acs.bioconjchem.8b00456. Epub 2018 Aug 23. Bioconjug Chem. 2018. PMID: 30105903

8

An EGFR-targeting antibody-drug conjugate LR004-VC-MMAE: potential in esophageal squamous cell carcinoma and other malignancies.

Hu XY, Wang R, Jin J, Liu XJ, Cui AL, Sun LQ, Li YP, Li Y, Wang YC, Zhen YS, Miao QF, Li ZR. Hu XY, et al. Among authors: li y, li yp, li zr. Mol Oncol. 2019 Feb;13(2):246-263. doi: 10.1002/1878-0261.12400. Epub 2018 Nov 15. Mol Oncol. 2019. PMID: 30372581 Free PMC article.

9

Internal enhancement of DNA damage by a novel bispecific antibody-drug conjugate-like therapeutics via blockage of mTOR and PD-L1 signal pathways in pancreatic cancer.

Cao R, Song W, Ye C, Liu X, Li L, Li Y, Yao H, Zhou X, Li L, Shao R. Cao R, et al. Among authors: li y, li l. Cancer Med. 2019 Feb;8(2):643-655. doi: 10.1002/cam4.1974. Epub 2019 Jan 25. Cancer Med. 2019. PMID: 30681288 Free PMC article.

10

Crizotinib enhances anti-CD30-LDM induced antitumor efficacy in NPM-ALK positive anaplastic large cell lymphoma.

Wang R, Li L, Duan A, Li Y, Liu X, Miao Q, Gong J, Zhen Y. Wang R, et al. Among authors: li y, li l. Cancer Lett. 2019 Apr 28;448:84-93. doi: 10.1016/j.canlet.2019.02.002. Epub 2019 Feb 8. Cancer Lett. 2019. PMID: 30742941

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