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Targeting MYC in combination with epigenetic regulators induces synergistic anti-leukemic effects in MLLr leukemia and simultaneously improves immunity.
Fitzel R, Secker-Grob KA, Keppeler H, Korkmaz F, Schairer R, Erkner E, Schneidawind D, Lengerke C, Hentrich T, Schulze-Hentrich JM, Schneidawind C. Fitzel R, et al. Among authors: keppeler h. Neoplasia. 2023 Jul;41:100902. doi: 10.1016/j.neo.2023.100902. Epub 2023 May 4. Neoplasia. 2023. PMID: 37148657 Free PMC article.
Sodium overload and water influx activate the NALP3 inflammasome.
Schorn C, Frey B, Lauber K, Janko C, Strysio M, Keppeler H, Gaipl US, Voll RE, Springer E, Munoz LE, Schett G, Herrmann M. Schorn C, et al. Among authors: keppeler h. J Biol Chem. 2011 Jan 7;286(1):35-41. doi: 10.1074/jbc.M110.139048. Epub 2010 Nov 4. J Biol Chem. 2011. PMID: 21051542 Free PMC article.
Phagocytosis of dying tumor cells by human peritoneal mesothelial cells.
Wagner BJ, Lindau D, Ripper D, Stierhof YD, Glatzle J, Witte M, Beck H, Keppeler H, Lauber K, Rammensee HG, Königsrainer A. Wagner BJ, et al. Among authors: keppeler h. J Cell Sci. 2011 May 15;124(Pt 10):1644-54. doi: 10.1242/jcs.078907. Epub 2011 Apr 26. J Cell Sci. 2011. PMID: 21525033
Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction.
Alers S, Löffler AS, Paasch F, Dieterle AM, Keppeler H, Lauber K, Campbell DG, Fehrenbacher B, Schaller M, Wesselborg S, Stork B. Alers S, et al. Among authors: keppeler h. Autophagy. 2011 Dec;7(12):1423-33. doi: 10.4161/auto.7.12.18027. Autophagy. 2011. PMID: 22024743 Free PMC article.
47 results