Patra KC - Search Results

1

Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin.

DeWaal D, Nogueira V, Terry AR, Patra KC, Jeon SM, Guzman G, Au J, Long CP, Antoniewicz MR, Hay N. DeWaal D, et al. Among authors: patra kc. Nat Commun. 2018 Jan 31;9(1):446. doi: 10.1038/s41467-017-02733-4. Nat Commun. 2018. PMID: 29386513 Free PMC article.

2

Hexokinase 2 as oncotarget.

Patra KC, Hay N. Patra KC, et al. Oncotarget. 2013 Nov;4(11):1862-3. doi: 10.18632/oncotarget.1563. Oncotarget. 2013. PMID: 24196563 Free PMC article. No abstract available.

3

Author Correction: Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin.

DeWaal D, Nogueira V, Terry AR, Patra KC, Jeon SM, Guzman G, Au J, Long CP, Antoniewicz MR, Hay N. DeWaal D, et al. Among authors: patra kc. Nat Commun. 2018 Jun 26;9(1):2539. doi: 10.1038/s41467-018-04182-z. Nat Commun. 2018. PMID: 29946147 Free PMC article.

4

A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis.

Blaha CS, Ramakrishnan G, Jeon SM, Nogueira V, Rho H, Kang S, Bhaskar P, Terry AR, Aissa AF, Frolov MV, Patra KC, Brooks Robey R, Hay N. Blaha CS, et al. Among authors: patra kc. Nat Commun. 2022 Feb 16;13(1):899. doi: 10.1038/s41467-022-28440-3. Nat Commun. 2022. PMID: 35173161 Free PMC article.

5

mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition.

Bhaskar PT, Nogueira V, Patra KC, Jeon SM, Park Y, Robey RB, Hay N. Bhaskar PT, et al. Among authors: patra kc. Mol Cell Biol. 2009 Sep;29(18):5136-47. doi: 10.1128/MCB.01946-08. Epub 2009 Jul 20. Mol Cell Biol. 2009. PMID: 19620286 Free PMC article.

6

The pentose phosphate pathway and cancer.

Patra KC, Hay N. Patra KC, et al. Trends Biochem Sci. 2014 Aug;39(8):347-54. doi: 10.1016/j.tibs.2014.06.005. Epub 2014 Jul 15. Trends Biochem Sci. 2014. PMID: 25037503 Free PMC article. Review.

7

Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation.

Nogueira V, Patra KC, Hay N. Nogueira V, et al. Among authors: patra kc. Elife. 2018 Apr 24;7:e32213. doi: 10.7554/eLife.32213. Elife. 2018. PMID: 29687779 Free PMC article.

8

Systemic Akt1 Deletion after Tumor Onset in p53(-/-) Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration.

Yu WN, Nogueira V, Sobhakumari A, Patra KC, Bhaskar PT, Hay N. Yu WN, et al. Among authors: patra kc. Cell Rep. 2015 Jul 28;12(4):610-21. doi: 10.1016/j.celrep.2015.06.057. Epub 2015 Jul 16. Cell Rep. 2015. PMID: 26190111 Free PMC article.

9

Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer.

Patra KC, Wang Q, Bhaskar PT, Miller L, Wang Z, Wheaton W, Chandel N, Laakso M, Muller WJ, Allen EL, Jha AK, Smolen GA, Clasquin MF, Robey B, Hay N. Patra KC, et al. Cancer Cell. 2013 Aug 12;24(2):213-228. doi: 10.1016/j.ccr.2013.06.014. Epub 2013 Aug 1. Cancer Cell. 2013. PMID: 23911236 Free PMC article.

10

Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.

Patra KC, Kato Y, Mizukami Y, Widholz S, Boukhali M, Revenco I, Grossman EA, Ji F, Sadreyev RI, Liss AS, Screaton RA, Sakamoto K, Ryan DP, Mino-Kenudson M, Castillo CF, Nomura DK, Haas W, Bardeesy N. Patra KC, et al. Nat Cell Biol. 2018 Jul;20(7):811-822. doi: 10.1038/s41556-018-0122-3. Epub 2018 Jun 25. Nat Cell Biol. 2018. PMID: 29941929 Free PMC article.

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