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Page 1
Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: a potential new approach for the treatment of hyperinsulinemic hypoglycemia.
Corbin JA, Bhaskar V, Goldfine ID, Issafras H, Bedinger DH, Lau A, Michelson K, Gross LM, Maddux BA, Kuan HF, Tran C, Lao L, Handa M, Watson SR, Narasimha AJ, Zhu S, Levy R, Webster L, Wijesuriya SD, Liu N, Wu X, Chemla-Vogel D, Lee SR, Wong S, Wilcock D, Rubin P, White ML. Corbin JA, et al. Among authors: bedinger dh. MAbs. 2014 Jan-Feb;6(1):262-72. doi: 10.4161/mabs.26871. MAbs. 2014. PMID: 24423625 Free PMC article.
Healthy humans can be a source of antibodies countering COVID-19.
Velappan N, Nguyen HB, Micheva-Viteva S, Bedinger D, Ye C, Mangadu B, Watts AJ, Meagher R, Bradfute S, Hu B, Waldo GS, Lillo AM. Velappan N, et al. Among authors: bedinger d. Bioengineered. 2022 May;13(5):12598-12624. doi: 10.1080/21655979.2022.2076390. Bioengineered. 2022. PMID: 35599623 Free PMC article.
Assessing the binding properties of the anti-PD-1 antibody landscape using label-free biosensors.
Brown ME, Bedinger D, Lilov A, Rathanaswami P, Vásquez M, Durand S, Wallace-Moyer I, Zhong L, Nett JH, Burnina I, Caffry I, Lynaugh H, Sinclair M, Sun T, Bukowski J, Xu Y, Abdiche YN. Brown ME, et al. Among authors: bedinger d. PLoS One. 2020 Mar 5;15(3):e0229206. doi: 10.1371/journal.pone.0229206. eCollection 2020. PLoS One. 2020. PMID: 32134960 Free PMC article.
Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity.
Roell MK, Issafras H, Bauer RJ, Michelson KS, Mendoza N, Vanegas SI, Gross LM, Larsen PD, Bedinger DH, Bohmann DJ, Nonet GH, Liu N, Lee SR, Handa M, Kantak SS, Horwitz AH, Hunter JJ, Owyang AM, Mirza AM, Corbin JA, White ML. Roell MK, et al. Among authors: bedinger dh. J Biol Chem. 2010 Jul 2;285(27):20607-14. doi: 10.1074/jbc.M110.115790. Epub 2010 Apr 21. J Biol Chem. 2010. PMID: 20410301 Free PMC article.
A fully human, allosteric monoclonal antibody that activates the insulin receptor and improves glycemic control.
Bhaskar V, Goldfine ID, Bedinger DH, Lau A, Kuan HF, Gross LM, Handa M, Maddux BA, Watson SR, Zhu S, Narasimha AJ, Levy R, Webster L, Wijesuriya SD, Liu N, Wu X, Chemla-Vogel D, Tran C, Lee SR, Wong S, Wilcock D, White ML, Corbin JA. Bhaskar V, et al. Among authors: bedinger dh. Diabetes. 2012 May;61(5):1263-71. doi: 10.2337/db11-1578. Epub 2012 Mar 8. Diabetes. 2012. PMID: 22403294 Free PMC article.
23 results