Mitsuya H - Search Results

1

HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir.

Yasutake Y, Hattori SI, Hayashi H, Matsuda K, Tamura N, Kohgo S, Maeda K, Mitsuya H. Yasutake Y, et al. Among authors: mitsuya h. Sci Rep. 2018 Jan 26;8(1):1624. doi: 10.1038/s41598-018-19602-9. Sci Rep. 2018. PMID: 29374261 Free PMC article.

2

Protein binding of human immunodeficiency virus protease inhibitor KNI-272 and alteration of its in vitro antiretroviral activity in the presence of high concentrations of proteins.

Kageyama S, Anderson BD, Hoesterey BL, Hayashi H, Kiso Y, Flora KP, Mitsuya H. Kageyama S, et al. Among authors: mitsuya h. Antimicrob Agents Chemother. 1994 May;38(5):1107-11. doi: 10.1128/AAC.38.5.1107. Antimicrob Agents Chemother. 1994. PMID: 8067746 Free PMC article.

3

Removal of human immunodeficiency virus type 1 (HIV-1) protease inhibitors from preparations of immature HIV-1 virions does not result in an increase in infectivity or the appearance of mature morphology.

Humphrey RW, Ohagen A, Davis DA, Fukazawa T, Hayashi H, Höglund S, Mitsuya H, Yarchoan R. Humphrey RW, et al. Among authors: mitsuya h. Antimicrob Agents Chemother. 1997 May;41(5):1017-23. doi: 10.1128/AAC.41.5.1017. Antimicrob Agents Chemother. 1997. PMID: 9145862 Free PMC article.

4

A phase I trial of the pharmacokinetics, toxicity, and activity of KNI-272, an inhibitor of HIV-1 protease, in patients with AIDS or symptomatic HIV infection.

Humphrey RW, Wyvill KM, Nguyen BY, Shay LE, Kohler DR, Steinberg SM, Ueno T, Fukasawa T, Shintani M, Hayashi H, Mitsuya H, Yarchoan R. Humphrey RW, et al. Among authors: mitsuya h. Antiviral Res. 1999 Feb;41(1):21-33. doi: 10.1016/s0166-3542(98)00058-8. Antiviral Res. 1999. PMID: 10321576 Clinical Trial.

5

JE-2147: a dipeptide protease inhibitor (PI) that potently inhibits multi-PI-resistant HIV-1.

Yoshimura K, Kato R, Yusa K, Kavlick MF, Maroun V, Nguyen A, Mimoto T, Ueno T, Shintani M, Falloon J, Masur H, Hayashi H, Erickson J, Mitsuya H. Yoshimura K, et al. Among authors: mitsuya h. Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8675-80. doi: 10.1073/pnas.96.15.8675. Proc Natl Acad Sci U S A. 1999. PMID: 10411934 Free PMC article.

6

4'-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitro.

Kodama EI, Kohgo S, Kitano K, Machida H, Gatanaga H, Shigeta S, Matsuoka M, Ohrui H, Mitsuya H. Kodama EI, et al. Among authors: mitsuya h. Antimicrob Agents Chemother. 2001 May;45(5):1539-46. doi: 10.1128/AAC.45.5.1539-1546.2001. Antimicrob Agents Chemother. 2001. PMID: 11302824 Free PMC article.

7

Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5.

Maeda K, Yoshimura K, Shibayama S, Habashita H, Tada H, Sagawa K, Miyakawa T, Aoki M, Fukushima D, Mitsuya H. Maeda K, et al. Among authors: mitsuya h. J Biol Chem. 2001 Sep 14;276(37):35194-200. doi: 10.1074/jbc.M105670200. Epub 2001 Jul 13. J Biol Chem. 2001. PMID: 11454872 Free article.

8

Synthesis of the L-enantiomer of 4'-C-ethynyl-2'-deoxycytidine.

Kohgo S, Mitsuya H, Ohrui H. Kohgo S, et al. Among authors: mitsuya h. Biosci Biotechnol Biochem. 2001 Aug;65(8):1879-82. doi: 10.1271/bbb.65.1879. Biosci Biotechnol Biochem. 2001. PMID: 11577734 Free article.

9

Identification of amino acid residues critical for LD78beta, a variant of human macrophage inflammatory protein-1alpha, binding to CCR5 and inhibition of R5 human immunodeficiency virus type 1 replication.

Miyakawa T, Obaru K, Maeda K, Harada S, Mitsuya H. Miyakawa T, et al. Among authors: mitsuya h. J Biol Chem. 2002 Feb 15;277(7):4649-55. doi: 10.1074/jbc.M109198200. Epub 2001 Dec 4. J Biol Chem. 2002. PMID: 11734558 Free article.

10

A potent human immunodeficiency virus type 1 protease inhibitor, UIC-94003 (TMC-126), and selection of a novel (A28S) mutation in the protease active site.

Yoshimura K, Kato R, Kavlick MF, Nguyen A, Maroun V, Maeda K, Hussain KA, Ghosh AK, Gulnik SV, Erickson JW, Mitsuya H. Yoshimura K, et al. Among authors: mitsuya h. J Virol. 2002 Feb;76(3):1349-58. doi: 10.1128/jvi.76.3.1349-1358.2002. J Virol. 2002. PMID: 11773409 Free PMC article.

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