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A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy.
Bryant KG, Chae YC, Martinez RL, Gordon JC, Elokely KM, Kossenkov AV, Grant S, Childers WE, Abou-Gharbia M, Altieri DC. Bryant KG, et al. Among authors: elokely km. Oncotarget. 2017 Dec 11;8(68):112184-112198. doi: 10.18632/oncotarget.23097. eCollection 2017 Dec 22. Oncotarget. 2017. PMID: 29348817 Free PMC article.
Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors.
Al-Ashmawy AAK, Ragab FA, Elokely KM, Anwar MM, Perez-Leal O, Rico MC, Gordon J, Bichenkov E, Mateo G, Kassem EMM, Hegazy GH, Abou-Gharbia M, Childers W. Al-Ashmawy AAK, et al. Among authors: elokely km. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3117-3122. doi: 10.1016/j.bmcl.2017.05.044. Epub 2017 May 15. Bioorg Med Chem Lett. 2017. PMID: 28571824
The Resurrection of Phenotypic Drug Discovery.
Childers WE, Elokely KM, Abou-Gharbia M. Childers WE, et al. Among authors: elokely km. ACS Med Chem Lett. 2020 Mar 6;11(10):1820-1828. doi: 10.1021/acsmedchemlett.0c00006. eCollection 2020 Oct 8. ACS Med Chem Lett. 2020. PMID: 33062159 Free PMC article.
40 results