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A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics.
Raskin A, Lange S, Banares K, Lyon RC, Zieseniss A, Lee LK, Yamazaki KG, Granzier HL, Gregorio CC, McCulloch AD, Omens JH, Sheikh F. Raskin A, et al. Among authors: sheikh f. J Biol Chem. 2012 Aug 24;287(35):29273-84. doi: 10.1074/jbc.M112.372839. Epub 2012 Jul 9. J Biol Chem. 2012. PMID: 22778266 Free PMC article.
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice.
Sheikh F, Raskin A, Chu PH, Lange S, Domenighetti AA, Zheng M, Liang X, Zhang T, Yajima T, Gu Y, Dalton ND, Mahata SK, Dorn GW 2nd, Brown JH, Peterson KL, Omens JH, McCulloch AD, Chen J. Sheikh F, et al. J Clin Invest. 2008 Dec;118(12):3870-80. doi: 10.1172/JCI34472. Epub 2008 Nov 3. J Clin Invest. 2008. PMID: 19033658 Free PMC article.
Breaking down protein degradation mechanisms in cardiac muscle.
Lyon RC, Lange S, Sheikh F. Lyon RC, et al. Among authors: sheikh f. Trends Mol Med. 2013 Apr;19(4):239-49. doi: 10.1016/j.molmed.2013.01.005. Epub 2013 Feb 27. Trends Mol Med. 2013. PMID: 23453282 Free PMC article. Review.
Mechanotransduction in cardiac hypertrophy and failure.
Lyon RC, Zanella F, Omens JH, Sheikh F. Lyon RC, et al. Among authors: sheikh f. Circ Res. 2015 Apr 10;116(8):1462-1476. doi: 10.1161/CIRCRESAHA.116.304937. Circ Res. 2015. PMID: 25858069 Free PMC article. Review.
Four and a half LIM domain protein signaling and cardiomyopathy.
Liang Y, Bradford WH, Zhang J, Sheikh F. Liang Y, et al. Among authors: sheikh f. Biophys Rev. 2018 Aug;10(4):1073-1085. doi: 10.1007/s12551-018-0434-3. Epub 2018 Jun 20. Biophys Rev. 2018. PMID: 29926425 Free PMC article. Review.
495 results