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Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells.
Konno M, Matsui H, Koseki J, Asai A, Kano Y, Kawamoto K, Nishida N, Sakai D, Kudo T, Satoh T, Doki Y, Mori M, Ishii H. Konno M, et al. Among authors: asai a. Sci Rep. 2018 Jan 17;8(1):899. doi: 10.1038/s41598-018-19284-3. Sci Rep. 2018. PMID: 29343747 Free PMC article.
Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells.
Toshiyama R, Konno M, Eguchi H, Takemoto H, Noda T, Asai A, Koseki J, Haraguchi N, Ueda Y, Matsushita K, Asukai K, Ohashi T, Iwagami Y, Yamada D, Sakai D, Asaoka T, Kudo T, Kawamoto K, Gotoh K, Kobayashi S, Satoh T, Doki Y, Nishiyama N, Mori M, Ishii H. Toshiyama R, et al. Among authors: asai a. Oncogene. 2019 Jan;38(2):244-260. doi: 10.1038/s41388-018-0406-x. Epub 2018 Aug 8. Oncogene. 2019. PMID: 30089817
Clinical Significance of Histone Demethylase NO66 in Invasive Colorectal Cancer.
Nishizawa Y, Nishida N, Konno M, Kawamoto K, Asai A, Koseki J, Takahashi H, Haraguchi N, Nishimura J, Hata T, Matsuda C, Mizushima T, Satoh T, Doki Y, Mori M, Ishii H. Nishizawa Y, et al. Among authors: asai a. Ann Surg Oncol. 2017 Mar;24(3):841-849. doi: 10.1245/s10434-016-5395-9. Epub 2016 Jul 29. Ann Surg Oncol. 2017. PMID: 27473587
686 results