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Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans.
Wong T, Wang Z, Chapron BD, Suzuki M, Claw KG, Gao C, Foti RS, Prasad B, Chapron A, Calamia J, Chaudhry A, Schuetz EG, Horst RL, Mao Q, de Boer IH, Thornton TA, Thummel KE. Wong T, et al. Among authors: thornton ta. Drug Metab Dispos. 2018 Apr;46(4):367-379. doi: 10.1124/dmd.117.078428. Epub 2018 Jan 17. Drug Metab Dispos. 2018. PMID: 29343609 Free PMC article.
Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content.
Shirasaka Y, Chaudhry AS, McDonald M, Prasad B, Wong T, Calamia JC, Fohner A, Thornton TA, Isoherranen N, Unadkat JD, Rettie AE, Schuetz EG, Thummel KE. Shirasaka Y, et al. Among authors: thornton ta. Pharmacogenomics J. 2016 Aug;16(4):375-87. doi: 10.1038/tpj.2015.58. Epub 2015 Sep 1. Pharmacogenomics J. 2016. PMID: 26323597 Free PMC article.
Genetics, Diet, and Season Are Associated with Serum 25-Hydroxycholecalciferol Concentration in a Yup'ik Study Population from Southwestern Alaska.
Fohner AE, Wang Z, Yracheta J, O'Brien DM, Hopkins SE, Black J, Philip J, Wiener HW, Tiwari HK, Stapleton PL, Tsai JM, Thornton TA, Boyer BB, Thummel KE. Fohner AE, et al. Among authors: thornton ta. J Nutr. 2016 Feb;146(2):318-25. doi: 10.3945/jn.115.223388. Epub 2015 Dec 9. J Nutr. 2016. PMID: 26661839 Free PMC article.
Dietary Vitamin K and Association with Hepatic Vitamin K Status in a Yup'ik Study Population from Southwestern Alaska.
Au NT, Ryman T, Rettie AE, Hopkins SE, Boyer BB, Black J, Philip J, Yracheta J, Fohner AE, Reyes M, Thornton TA, Austin MA, Thummel KE. Au NT, et al. Among authors: thornton ta. Mol Nutr Food Res. 2018 Feb;62(3):10.1002/mnfr.201700746. doi: 10.1002/mnfr.201700746. Epub 2017 Dec 29. Mol Nutr Food Res. 2018. PMID: 29094808 Free PMC article.
Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex.
Bhatt DK, Basit A, Zhang H, Gaedigk A, Lee SB, Claw KG, Mehrotra A, Chaudhry AS, Pearce RE, Gaedigk R, Broeckel U, Thornton TA, Nickerson DA, Schuetz EG, Amory JK, Leeder JS, Prasad B. Bhatt DK, et al. Among authors: thornton ta. Drug Metab Dispos. 2018 Jun;46(6):888-896. doi: 10.1124/dmd.118.080952. Epub 2018 Mar 30. Drug Metab Dispos. 2018. PMID: 29602798 Free PMC article.
Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6-Mediated Metabolic Activity.
Dalton R, Lee SB, Claw KG, Prasad B, Phillips BR, Shen DD, Wong LH, Fade M, McDonald MG, Dunham MJ, Fowler DM, Rettie AE, Schuetz E, Thornton TA, Nickerson DA, Gaedigk A, Thummel KE, Woodahl EL. Dalton R, et al. Among authors: thornton ta. Clin Transl Sci. 2020 Jan;13(1):147-156. doi: 10.1111/cts.12695. Epub 2019 Oct 25. Clin Transl Sci. 2020. PMID: 31536170 Free PMC article.
Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function.
Fohner AE, Dalton R, Skagen K, Jackson K, Claw KG, Hopkins SE, Robinson R, Khan BA, Prasad B, Schuetz EG, Nickerson DA, Thornton TA, Dillard DA, Boyer BB, Thummel KE, Woodahl EL. Fohner AE, et al. Among authors: thornton ta. Clin Transl Sci. 2021 Jul;14(4):1292-1302. doi: 10.1111/cts.12970. Epub 2021 Jan 27. Clin Transl Sci. 2021. PMID: 33503331 Free PMC article.
188 results