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Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans.
Wong T, Wang Z, Chapron BD, Suzuki M, Claw KG, Gao C, Foti RS, Prasad B, Chapron A, Calamia J, Chaudhry A, Schuetz EG, Horst RL, Mao Q, de Boer IH, Thornton TA, Thummel KE. Wong T, et al. Among authors: schuetz eg. Drug Metab Dispos. 2018 Apr;46(4):367-379. doi: 10.1124/dmd.117.078428. Epub 2018 Jan 17. Drug Metab Dispos. 2018. PMID: 29343609 Free PMC article.
Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism.
Tracy TS, Chaudhry AS, Prasad B, Thummel KE, Schuetz EG, Zhong XB, Tien YC, Jeong H, Pan X, Shireman LM, Tay-Sontheimer J, Lin YS. Tracy TS, et al. Among authors: schuetz eg. Drug Metab Dispos. 2016 Mar;44(3):343-51. doi: 10.1124/dmd.115.067900. Epub 2015 Dec 17. Drug Metab Dispos. 2016. PMID: 26681736 Free PMC article. Review.
Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex.
Bhatt DK, Basit A, Zhang H, Gaedigk A, Lee SB, Claw KG, Mehrotra A, Chaudhry AS, Pearce RE, Gaedigk R, Broeckel U, Thornton TA, Nickerson DA, Schuetz EG, Amory JK, Leeder JS, Prasad B. Bhatt DK, et al. Among authors: schuetz eg. Drug Metab Dispos. 2018 Jun;46(6):888-896. doi: 10.1124/dmd.118.080952. Epub 2018 Mar 30. Drug Metab Dispos. 2018. PMID: 29602798 Free PMC article.
The influence of CYP3A5 expression on the extent of hepatic CYP3A inhibition is substrate-dependent: an in vitro-in vivo evaluation.
Isoherranen N, Ludington SR, Givens RC, Lamba JK, Pusek SN, Dees EC, Blough DK, Iwanaga K, Hawke RL, Schuetz EG, Watkins PB, Thummel KE, Paine MF. Isoherranen N, et al. Among authors: schuetz eg. Drug Metab Dispos. 2008 Jan;36(1):146-54. doi: 10.1124/dmd.107.018382. Epub 2007 Oct 22. Drug Metab Dispos. 2008. PMID: 17954524
Interplay between vitamin D and the drug metabolizing enzyme CYP3A4.
Wang Z, Schuetz EG, Xu Y, Thummel KE. Wang Z, et al. Among authors: schuetz eg. J Steroid Biochem Mol Biol. 2013 Jul;136:54-8. doi: 10.1016/j.jsbmb.2012.09.012. Epub 2012 Sep 15. J Steroid Biochem Mol Biol. 2013. PMID: 22985909 Free PMC article. Review.
Why do most human liver cytosol preparations lack xanthine oxidase activity?
Barr JT, Choughule KV, Nepal S, Wong T, Chaudhry AS, Joswig-Jones CA, Zientek M, Strom SC, Schuetz EG, Thummel KE, Jones JP. Barr JT, et al. Among authors: schuetz eg. Drug Metab Dispos. 2014 Apr;42(4):695-9. doi: 10.1124/dmd.113.056374. Epub 2014 Jan 15. Drug Metab Dispos. 2014. PMID: 24430612 Free PMC article.
199 results