Blaesse M - Search Results

1

Molecular Insights into Function and Competitive Inhibition of Pseudomonas aeruginosa Multiple Virulence Factor Regulator.

Kitao T, Lepine F, Babloudi S, Walte F, Steinbacher S, Maskos K, Blaesse M, Negri M, Pucci M, Zahler B, Felici A, Rahme LG. Kitao T, et al. Among authors: blaesse m. mBio. 2018 Jan 16;9(1):e02158-17. doi: 10.1128/mBio.02158-17. mBio. 2018. PMID: 29339431 Free PMC article.

2

The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder.

Schneider EV, Böttcher J, Blaesse M, Neumann L, Huber R, Maskos K. Schneider EV, et al. Among authors: blaesse m. J Mol Biol. 2011 Sep 16;412(2):251-66. doi: 10.1016/j.jmb.2011.07.020. Epub 2011 Jul 23. J Mol Biol. 2011. PMID: 21806996

3

Structure of MrsD, an FAD-binding protein of the HFCD family.

Blaesse M, Kupke T, Huber R, Steinbacher S. Blaesse M, et al. Acta Crystallogr D Biol Crystallogr. 2003 Aug;59(Pt 8):1414-21. doi: 10.1107/s0907444903011831. Epub 2003 Jul 23. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 12876343

4

Crystal structure of the peptidyl-cysteine decarboxylase EpiD complexed with a pentapeptide substrate.

Blaesse M, Kupke T, Huber R, Steinbacher S. Blaesse M, et al. EMBO J. 2000 Dec 1;19(23):6299-310. doi: 10.1093/emboj/19.23.6299. EMBO J. 2000. PMID: 11101502 Free PMC article.

5

Crystal structure of the plant PPC decarboxylase AtHAL3a complexed with an ene-thiol reaction intermediate.

Steinbacher S, Hernández-Acosta P, Bieseler B, Blaesse M, Huber R, Culiáñez-Macià FA, Kupke T. Steinbacher S, et al. Among authors: blaesse m. J Mol Biol. 2003 Mar 14;327(1):193-202. doi: 10.1016/s0022-2836(03)00092-5. J Mol Biol. 2003. PMID: 12614618

6

Design and Evaluation of Highly Selective Human Immunoproteasome Inhibitors Reveal a Compensatory Process That Preserves Immune Cell Viability.

Ladi E, Everett C, Stivala CE, Daniels BE, Durk MR, Harris SF, Huestis MP, Purkey HE, Staben ST, Augustin M, Blaesse M, Steinbacher S, Eidenschenk C, Pappu R, Siu M. Ladi E, et al. Among authors: blaesse m. J Med Chem. 2019 Aug 8;62(15):7032-7041. doi: 10.1021/acs.jmedchem.9b00509. Epub 2019 Jul 29. J Med Chem. 2019. PMID: 31283222

7

Molecular characterization of lantibiotic-synthesizing enzyme EpiD reveals a function for bacterial Dfp proteins in coenzyme A biosynthesis.

Kupke T, Uebele M, Schmid D, Jung G, Blaesse M, Steinbacher S. Kupke T, et al. Among authors: blaesse m. J Biol Chem. 2000 Oct 13;275(41):31838-46. doi: 10.1074/jbc.M004273200. J Biol Chem. 2000. PMID: 10922366 Free article.

8

Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies.

Grädler U, Schwarz D, Blaesse M, Leuthner B, Johnson TL, Bernard F, Jiang X, Marx A, Gilardone M, Lemoine H, Roche D, Jorand-Lebrun C. Grädler U, et al. Among authors: blaesse m. Bioorg Med Chem Lett. 2019 Dec 1;29(23):126717. doi: 10.1016/j.bmcl.2019.126717. Epub 2019 Oct 16. Bioorg Med Chem Lett. 2019. PMID: 31635932 Free PMC article.

9

Crystal structure of ATP sulfurylase from Saccharomyces cerevisiae, a key enzyme in sulfate activation.

Ullrich TC, Blaesse M, Huber R. Ullrich TC, et al. Among authors: blaesse m. EMBO J. 2001 Feb 1;20(3):316-29. doi: 10.1093/emboj/20.3.316. EMBO J. 2001. PMID: 11157739 Free PMC article.

10

Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors.

Kalliokoski T, Rummakko P, Rantanen M, Blaesse M, Augustin M, Ummenthala GR, Choudhary S, Venäläinen J. Kalliokoski T, et al. Among authors: blaesse m. Bioorg Med Chem Lett. 2020 Apr 15;30(8):127060. doi: 10.1016/j.bmcl.2020.127060. Epub 2020 Feb 22. Bioorg Med Chem Lett. 2020. PMID: 32113843

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