Gao T - Search Results

1

Beta-catenin cleavage enhances transcriptional activation.

Goretsky T, Bradford EM, Ye Q, Lamping OF, Vanagunas T, Moyer MP, Keller PC, Sinh P, Llovet JM, Gao T, She QB, Li L, Barrett TA. Goretsky T, et al. Among authors: gao t. Sci Rep. 2018 Jan 12;8(1):671. doi: 10.1038/s41598-017-18421-8. Sci Rep. 2018. PMID: 29330435 Free PMC article.

2

Loss of PHLPP protects against colitis by inhibiting intestinal epithelial cell apoptosis.

Wen YA, Li X, Goretsky T, Weiss HL, Barrett TA, Gao T. Wen YA, et al. Among authors: gao t. Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2013-23. doi: 10.1016/j.bbadis.2015.07.012. Epub 2015 Jul 15. Biochim Biophys Acta. 2015. PMID: 26187040 Free PMC article.

3

A Cytosolic Multiprotein Complex Containing p85α Is Required for β-Catenin Activation in Colitis and Colitis-associated Cancer.

Goretsky T, Bradford EM, Ryu H, Tahir M, Moyer MP, Gao T, Li L, Barrett TA. Goretsky T, et al. Among authors: gao t. J Biol Chem. 2016 Feb 19;291(8):4166-77. doi: 10.1074/jbc.M115.669416. Epub 2015 Nov 12. J Biol Chem. 2016. PMID: 26565021 Free PMC article.

4

The mitochondrial retrograde signaling regulates Wnt signaling to promote tumorigenesis in colon cancer.

Wen YA, Xiong X, Scott T, Li AT, Wang C, Weiss HL, Tan L, Bradford E, Fan TWM, Chandel NS, Barrett TA, Gao T. Wen YA, et al. Among authors: gao t. Cell Death Differ. 2019 Oct;26(10):1955-1969. doi: 10.1038/s41418-018-0265-6. Epub 2019 Jan 18. Cell Death Differ. 2019. PMID: 30659235 Free PMC article.

5

Upregulation of Fatty Acid Synthase Increases Activity of β-Catenin and Expression of NOTUM to Enhance Stem-like Properties of Colorectal Cancer Cells.

Kelson CO, Tessmann JW, Geisen ME, He D, Wang C, Gao T, Evers BM, Zaytseva YY. Kelson CO, et al. Among authors: gao t. Cells. 2024 Oct 8;13(19):1663. doi: 10.3390/cells13191663. Cells. 2024. PMID: 39404424 Free PMC article.

6

Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer.

Gulhati P, Cai Q, Li J, Liu J, Rychahou PG, Qiu S, Lee EY, Silva SR, Bowen KA, Gao T, Evers BM. Gulhati P, et al. Among authors: gao t. Clin Cancer Res. 2009 Dec 1;15(23):7207-16. doi: 10.1158/1078-0432.CCR-09-1249. Epub 2009 Nov 24. Clin Cancer Res. 2009. PMID: 19934294 Free PMC article.

7

mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.

Gulhati P, Bowen KA, Liu J, Stevens PD, Rychahou PG, Chen M, Lee EY, Weiss HL, O'Connor KL, Gao T, Evers BM. Gulhati P, et al. Among authors: gao t. Cancer Res. 2011 May 1;71(9):3246-56. doi: 10.1158/0008-5472.CAN-10-4058. Epub 2011 Mar 23. Cancer Res. 2011. PMID: 21430067 Free PMC article.

8

Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt.

Li X, Yang H, Liu J, Schmidt MD, Gao T. Li X, et al. Among authors: gao t. EMBO Rep. 2011 Jun 24;12(8):818-24. doi: 10.1038/embor.2011.106. EMBO Rep. 2011. PMID: 21701506 Free PMC article.

9

The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer.

Li X, Stevens PD, Yang H, Gulhati P, Wang W, Evers BM, Gao T. Li X, et al. Among authors: gao t. Oncogene. 2013 Jan 24;32(4):471-8. doi: 10.1038/onc.2012.66. Epub 2012 Mar 5. Oncogene. 2013. PMID: 22391563 Free PMC article.

10

Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA.

Gulhati P, Zaytseva YY, Valentino JD, Stevens PD, Kim JT, Sasazuki T, Shirasawa S, Lee EY, Weiss HL, Dong J, Gao T, Evers BM. Gulhati P, et al. Among authors: gao t. Carcinogenesis. 2012 Sep;33(9):1782-90. doi: 10.1093/carcin/bgs203. Epub 2012 Jun 13. Carcinogenesis. 2012. PMID: 22696593 Free PMC article.

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