Hara H - Search Results

1

GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose.

Iwasaki Y, Sendo M, Dezaki K, Hira T, Sato T, Nakata M, Goswami C, Aoki R, Arai T, Kumari P, Hayakawa M, Masuda C, Okada T, Hara H, Drucker DJ, Yamada Y, Tokuda M, Yada T. Iwasaki Y, et al. Among authors: hara h. Nat Commun. 2018 Jan 9;9(1):113. doi: 10.1038/s41467-017-02488-y. Nat Commun. 2018. PMID: 29317623 Free PMC article.

2

GLP-1 secretion is enhanced directly in the ileum but indirectly in the duodenum by a newly identified potent stimulator, zein hydrolysate, in rats.

Hira T, Mochida T, Miyashita K, Hara H. Hira T, et al. Among authors: hara h. Am J Physiol Gastrointest Liver Physiol. 2009 Oct;297(4):G663-71. doi: 10.1152/ajpgi.90635.2008. Epub 2009 Aug 6. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19661152 Free article.

3

The corn protein, zein hydrolysate, administered into the ileum attenuates hyperglycemia via its dual action on glucagon-like peptide-1 secretion and dipeptidyl peptidase-IV activity in rats.

Mochida T, Hira T, Hara H. Mochida T, et al. Among authors: hara h. Endocrinology. 2010 Jul;151(7):3095-104. doi: 10.1210/en.2009-1510. Epub 2010 Apr 21. Endocrinology. 2010. PMID: 20410194 Free article.

4

GLP-1 secretion in response to oral and luminal palatinose (isomaltulose) in rats.

Hira T, Muramatsu M, Okuno M, Hara H. Hira T, et al. Among authors: hara h. J Nutr Sci Vitaminol (Tokyo). 2011;57(1):30-5. doi: 10.3177/jnsv.57.30. J Nutr Sci Vitaminol (Tokyo). 2011. PMID: 21512288 Free article.

5

Oral administration of corn zein hydrolysate stimulates GLP-1 and GIP secretion and improves glucose tolerance in male normal rats and Goto-Kakizaki rats.

Higuchi N, Hira T, Yamada N, Hara H. Higuchi N, et al. Among authors: hara h. Endocrinology. 2013 Sep;154(9):3089-98. doi: 10.1210/en.2012-2275. Epub 2013 Jun 24. Endocrinology. 2013. PMID: 23798598 Free article.

6

A nondigestible saccharide, fructooligosaccharide, increases the promotive effect of a flavonoid, α-glucosyl-isoquercitrin, on glucagon-like peptide 1 (GLP-1) secretion in rat intestine and enteroendocrine cells.

Phuwamongkolwiwat P, Hira T, Hara H. Phuwamongkolwiwat P, et al. Among authors: hara h. Mol Nutr Food Res. 2014 Jul;58(7):1581-4. doi: 10.1002/mnfr.201300871. Epub 2014 Apr 22. Mol Nutr Food Res. 2014. PMID: 24753209

7

Postprandial glucagon-like peptide-1 secretion is increased during the progression of glucose intolerance and obesity in high-fat/high-sucrose diet-fed rats.

Nakajima S, Hira T, Hara H. Nakajima S, et al. Among authors: hara h. Br J Nutr. 2015 May 14;113(9):1477-88. doi: 10.1017/S0007114515000550. Epub 2015 Apr 1. Br J Nutr. 2015. PMID: 25827219 Free article.

8

Canagliflozin potentiates GLP-1 secretion and lowers the peak of GIP secretion in rats fed a high-fat high-sucrose diet.

Hira T, Koga T, Sasaki K, Hara H. Hira T, et al. Among authors: hara h. Biochem Biophys Res Commun. 2017 Oct 14;492(2):161-165. doi: 10.1016/j.bbrc.2017.08.031. Epub 2017 Aug 10. Biochem Biophys Res Commun. 2017. PMID: 28803984 Free article.

9

Secretion of GLP-1 but not GIP is potently stimulated by luminal d-Allulose (d-Psicose) in rats.

Hayakawa M, Hira T, Nakamura M, Iida T, Kishimoto Y, Hara H. Hayakawa M, et al. Among authors: hara h. Biochem Biophys Res Commun. 2018 Feb 2:S0006-291X(18)30143-8. doi: 10.1016/j.bbrc.2018.01.128. Online ahead of print. Biochem Biophys Res Commun. 2018. PMID: 29402406

10

Continuous feeding of a combined high-fat and high-sucrose diet, rather than an individual high-fat or high-sucrose diet, rapidly enhances the glucagon-like peptide-1 secretory response to meal ingestion in diet-induced obese rats.

Pinyo J, Hira T, Hara H. Pinyo J, et al. Among authors: hara h. Nutrition. 2019 Jun;62:122-130. doi: 10.1016/j.nut.2019.01.004. Epub 2019 Jan 11. Nutrition. 2019. PMID: 30878816 Free article.

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