Wang D - Search Results

1

Discovery of EBI-1051: A novel and orally efficacious MEK inhibitor with benzofuran scaffold.

Lu B, Huang S, Cao J, Hu Q, Shen R, Wan H, Wang D, Yuan J, Zhang L, Zhang J, Zhang M, Tao W, Zhang L. Lu B, et al. Among authors: wang d. Bioorg Med Chem. 2018 Feb 1;26(3):581-589. doi: 10.1016/j.bmc.2017.12.019. Epub 2017 Dec 20. Bioorg Med Chem. 2018. PMID: 29317148

2

Structure-based design and synthesis of bicyclic fused-pyridines as MEK inhibitors.

Lu H, Tu W, Fei H, Xu G, Hu Q, Zhang L, Lin B, Yuan J, Yin J, Gong A, Wan M, Wang D, Zhu X, Feng J, Wang Q, Sun P. Lu H, et al. Among authors: wang d, wang q. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2555-9. doi: 10.1016/j.bmcl.2014.03.086. Epub 2014 Apr 3. Bioorg Med Chem Lett. 2014. PMID: 24755426

3

Discovery of EBI-907: A highly potent and orally active B-Raf(V600E) inhibitor for the treatment of melanoma and associated cancers.

Lu B, Cao H, Cao J, Huang S, Hu Q, Liu D, Shen R, Shen X, Tao W, Wan H, Wang D, Yan Y, Yang L, Zhang J, Zhang L, Zhang L, Zhang M. Lu B, et al. Among authors: wang d. Bioorg Med Chem Lett. 2016 Feb 1;26(3):819-823. doi: 10.1016/j.bmcl.2015.12.086. Epub 2015 Dec 24. Bioorg Med Chem Lett. 2016. PMID: 26739779

4

Discovery of EBI-2511: A Highly Potent and Orally Active EZH2 Inhibitor for the Treatment of Non-Hodgkin's Lymphoma.

Lu B, Shen X, Zhang L, Liu D, Zhang C, Cao J, Shen R, Zhang J, Wang D, Wan H, Xu Z, Ho MH, Zhang M, Zhang L, He F, Tao W. Lu B, et al. Among authors: wang d. ACS Med Chem Lett. 2018 Jan 29;9(2):98-102. doi: 10.1021/acsmedchemlett.7b00437. eCollection 2018 Feb 8. ACS Med Chem Lett. 2018. PMID: 29456795 Free PMC article.

5

Discovery of (Z)-1-(3-((1H-Pyrrol-2-yl)methylene)-2-oxoindolin-6-yl)-3-(isoxazol-3-yl)urea Derivatives as Novel and Orally Highly Effective CSF-1R Inhibitors for Potential Colorectal Cancer Immunotherapy.

Lv Q, Pan X, Wang D, Rong Q, Ma B, Xie X, Zhang Y, Wang J, Hu L. Lv Q, et al. Among authors: wang j, wang d. J Med Chem. 2021 Dec 9;64(23):17184-17208. doi: 10.1021/acs.jmedchem.1c01184. Epub 2021 Nov 4. J Med Chem. 2021. PMID: 34735158

6

Design, synthesis and biological evaluation of nitrofuran-1,3,4-oxadiazole hybrids as new antitubercular agents.

Wang A, Xu S, Chai Y, Xia G, Wang B, Lv K, Wang D, Qin X, Jiang B, Wu W, Liu M, Lu Y. Wang A, et al. Among authors: wang d, wang b. Bioorg Med Chem. 2022 Jan 1;53:116529. doi: 10.1016/j.bmc.2021.116529. Epub 2021 Nov 25. Bioorg Med Chem. 2022. PMID: 34861474

7

Design, synthesis, and evaluation of new endomorphin analogs with enhanced central antinociception after peripheral administration.

Liu X, Zhao L, Wang Y, Mou L, Yang J, Zhang Y, Wang D, Wang R. Liu X, et al. Among authors: wang y, wang d, wang r. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5393-7. doi: 10.1016/j.bmcl.2015.09.025. Epub 2015 Sep 11. Bioorg Med Chem Lett. 2015. PMID: 26403932

8

Controlling Energy Radiations of Electromagnetic Waves via Frequency Coding Metamaterials.

Wu H, Liu S, Wan X, Zhang L, Wang D, Li L, Cui TJ. Wu H, et al. Among authors: wang d. Adv Sci (Weinh). 2017 May 26;4(9):1700098. doi: 10.1002/advs.201700098. eCollection 2017 Sep. Adv Sci (Weinh). 2017. PMID: 28932671 Free PMC article.

9

Recent advances in microtubule-stabilizing agents.

Cao YN, Zheng LL, Wang D, Liang XX, Gao F, Zhou XL. Cao YN, et al. Among authors: wang d. Eur J Med Chem. 2018 Jan 1;143:806-828. doi: 10.1016/j.ejmech.2017.11.062. Epub 2017 Nov 24. Eur J Med Chem. 2018. PMID: 29223097 Review.

10

Discovery of a novel water-soluble, rapid-release triptolide prodrug with improved drug-like properties and high efficacy in human acute myeloid leukemia.

Kang D, Pan X, Song Y, Liu Y, Wang D, Zhu X, Wang J, Hu L. Kang D, et al. Among authors: wang j, wang d. Eur J Med Chem. 2022 Dec 5;243:114694. doi: 10.1016/j.ejmech.2022.114694. Epub 2022 Sep 5. Eur J Med Chem. 2022. PMID: 36115206

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