Lu B - Search Results

1

Discovery of EBI-1051: A novel and orally efficacious MEK inhibitor with benzofuran scaffold.

Lu B, Huang S, Cao J, Hu Q, Shen R, Wan H, Wang D, Yuan J, Zhang L, Zhang J, Zhang M, Tao W, Zhang L. Lu B, et al. Bioorg Med Chem. 2018 Feb 1;26(3):581-589. doi: 10.1016/j.bmc.2017.12.019. Epub 2017 Dec 20. Bioorg Med Chem. 2018. PMID: 29317148

2

Discovery of EBI-907: A highly potent and orally active B-Raf(V600E) inhibitor for the treatment of melanoma and associated cancers.

Lu B, Cao H, Cao J, Huang S, Hu Q, Liu D, Shen R, Shen X, Tao W, Wan H, Wang D, Yan Y, Yang L, Zhang J, Zhang L, Zhang L, Zhang M. Lu B, et al. Bioorg Med Chem Lett. 2016 Feb 1;26(3):819-823. doi: 10.1016/j.bmcl.2015.12.086. Epub 2015 Dec 24. Bioorg Med Chem Lett. 2016. PMID: 26739779

3

EBI-907, a novel BRAF(V600E) inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile.

Zhang J, Lu B, Liu D, Shen R, Yan Y, Yang L, Zhang M, Zhang L, Cao G, Cao H, Fu B, Gong A, Sun Q, Wan H, Zhang L, Tao W, Cao J. Zhang J, et al. Among authors: lu b. Cancer Biol Ther. 2016;17(2):199-207. doi: 10.1080/15384047.2016.1139231. Epub 2016 Jan 25. Cancer Biol Ther. 2016. PMID: 26810733 Free PMC article.

4

Discovery of EBI-2511: A Highly Potent and Orally Active EZH2 Inhibitor for the Treatment of Non-Hodgkin's Lymphoma.

Lu B, Shen X, Zhang L, Liu D, Zhang C, Cao J, Shen R, Zhang J, Wang D, Wan H, Xu Z, Ho MH, Zhang M, Zhang L, He F, Tao W. Lu B, et al. ACS Med Chem Lett. 2018 Jan 29;9(2):98-102. doi: 10.1021/acsmedchemlett.7b00437. eCollection 2018 Feb 8. ACS Med Chem Lett. 2018. PMID: 29456795 Free PMC article.

5

Discovery of 2-(Ortho-Substituted Benzyl)-Indole Derivatives as Potent and Orally Bioavailable RORγ Agonists with Antitumor Activity.

Lu B, Liu D, Gui B, Gou J, Dong H, Hu Q, Feng J, Mao Y, Shen X, Wang S, Zhang C, Shen R, Yan Y, Chen L, Wang H, Li D, Zhang J, Zhang M, Zhang R, Bai C, He F, Tao W, Liu S. Lu B, et al. J Med Chem. 2021 Oct 28;64(20):14983-14996. doi: 10.1021/acs.jmedchem.1c00828. Epub 2021 Oct 13. J Med Chem. 2021. PMID: 34643383

6

Design, Biological Characterization, and Discovery of Novel Cyclohexenyl Derivatives as Kinesin KIF18A Inhibitors for the Treatment of Ovarian Cancer.

Zhang C, Tu P, Jia X, Xia Y, Lu B, Yang F, Wang S, Jin L. Zhang C, et al. Among authors: lu b. ACS Med Chem Lett. 2024 Sep 17;15(10):1778-1786. doi: 10.1021/acsmedchemlett.4c00383. eCollection 2024 Oct 10. ACS Med Chem Lett. 2024. PMID: 39411524

7

Comparison of Remimazolam-Flumazenil and Propofol on Psychomotor Function and Emergence Following General Anesthesia in Surgical Abortion: A Randomized Controlled Trial.

Gu J, Liu Y, Lin X, Fu L, Liu J, Sun B, Li X, Lu B. Gu J, et al. Among authors: lu b. Drug Des Devel Ther. 2024 Dec 30;18:6447-6457. doi: 10.2147/DDDT.S486892. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 39758228 Free PMC article. Clinical Trial.

8

DNA palette code for time-series archival data storage.

Yan Z, Zhang H, Lu B, Han T, Tong X, Yuan Y. Yan Z, et al. Among authors: lu b. Natl Sci Rev. 2024 Sep 10;12(1):nwae321. doi: 10.1093/nsr/nwae321. eCollection 2025 Jan. Natl Sci Rev. 2024. PMID: 39758123 Free PMC article.

9

Enhancement of Osseointegration via Endogenous Electric Field by Regulating the Charge Microenvironments around Implants.

Xu F, Zhao G, Gong Y, Liang X, Yu M, Cui H, Xie L, Zhu N, Zhu X, Shao X, Qi K, Lu B, Tu J, Na S. Xu F, et al. Among authors: lu b. Adv Healthc Mater. 2025 Jan 5:e2403388. doi: 10.1002/adhm.202403388. Online ahead of print. Adv Healthc Mater. 2025. PMID: 39757756

10

Passive Isothermal Flexible Sensor Enabled by Smart Thermal-Regulating Aerogels.

Zhong S, Lu B, Wang DC, Arianpour B, Wang S, Han H, Yin J, Bao H, Liu Y, Wen Z, Zhou Y. Zhong S, et al. Among authors: lu b. Adv Mater. 2025 Jan 5:e2415386. doi: 10.1002/adma.202415386. Online ahead of print. Adv Mater. 2025. PMID: 39757553

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