Murray BP - Search Results

1

Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development.

Zheng J, Xin Y, Zhang J, Subramanian R, Murray BP, Whitney JA, Warr MR, Ling J, Moorehead L, Kwan E, Hemenway J, Smith BJ, Silverman JA. Zheng J, et al. Among authors: murray bp. Drug Metab Dispos. 2018 Mar;46(3):237-247. doi: 10.1124/dmd.117.078899. Epub 2018 Jan 8. Drug Metab Dispos. 2018. PMID: 29311136

2

Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase.

Fenaux M, Eng S, Leavitt SA, Lee YJ, Mabery EM, Tian Y, Byun D, Canales E, Clarke MO, Doerffler E, Lazerwith SE, Lew W, Liu Q, Mertzman M, Morganelli P, Xu L, Ye H, Zhang J, Matles M, Murray BP, Mwangi J, Zhang J, Hashash A, Krawczyk SH, Bidgood AM, Appleby TC, Watkins WJ. Fenaux M, et al. Among authors: murray bp. Antimicrob Agents Chemother. 2013 Feb;57(2):804-10. doi: 10.1128/AAC.02052-12. Epub 2012 Nov 26. Antimicrob Agents Chemother. 2013. PMID: 23183437 Free PMC article. Clinical Trial.

3

The Drug-Drug Interaction Profile of Presatovir.

Xin Y, Weng W, Murray BP, Eisenberg EJ, Chien JW, Ling J, Silverman JA. Xin Y, et al. Among authors: murray bp. J Clin Pharmacol. 2018 Jun;58(6):771-780. doi: 10.1002/jcph.1073. Epub 2018 Feb 7. J Clin Pharmacol. 2018. PMID: 29412463 Clinical Trial.

4

Pharmacokinetics and Safety of Velpatasvir and Sofosbuvir/Velpatasvir in Subjects with Hepatic Impairment.

Mogalian E, Brainard DM, Osinusi A, Moorehead L, Murray B, Ling KHJ, Perry R, Curtis C, Lawitz E, Lasseter K, Marbury T, Mathias A. Mogalian E, et al. Clin Pharmacokinet. 2018 Nov;57(11):1449-1457. doi: 10.1007/s40262-018-0645-6. Clin Pharmacokinet. 2018. PMID: 29520729 Clinical Trial.

5

Regional Proteomic Quantification of Clinically Relevant Non-Cytochrome P450 Enzymes along the Human Small Intestine.

Zhang H, Wolford C, Basit A, Li AP, Fan PW, Murray BP, Takahashi RH, Khojasteh SC, Smith BJ, Thummel KE, Prasad B. Zhang H, et al. Among authors: murray bp. Drug Metab Dispos. 2020 Jul;48(7):528-536. doi: 10.1124/dmd.120.090738. Epub 2020 Apr 29. Drug Metab Dispos. 2020. PMID: 32350063

6

Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human.

Basit A, Neradugomma NK, Wolford C, Fan PW, Murray B, Takahashi RH, Khojasteh SC, Smith BJ, Heyward S, Totah RA, Kelly EJ, Prasad B. Basit A, et al. Mol Pharm. 2020 Nov 2;17(11):4114-4124. doi: 10.1021/acs.molpharmaceut.0c00559. Epub 2020 Oct 2. Mol Pharm. 2020. PMID: 32955894

7

Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells.

Li R, Liclican A, Xu Y, Pitts J, Niu C, Zhang J, Kim C, Zhao X, Soohoo D, Babusis D, Yue Q, Ma B, Murray BP, Subramanian R, Xie X, Zou J, Bilello JP, Li L, Schultz BE, Sakowicz R, Smith BJ, Shi PY, Murakami E, Feng JY. Li R, et al. Among authors: murray bp. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0060221. doi: 10.1128/AAC.00602-21. Epub 2021 Aug 17. Antimicrob Agents Chemother. 2021. PMID: 34125594 Free PMC article.

8

Comparison of Tissue Abundance of Non-Cytochrome P450 Drug-Metabolizing Enzymes by Quantitative Proteomics between Humans and Laboratory Animal Species.

Basit A, Fan PW, Khojasteh SC, Murray BP, Smith BJ, Heyward S, Prasad B. Basit A, et al. Among authors: murray bp. Drug Metab Dispos. 2022 Mar;50(3):197-203. doi: 10.1124/dmd.121.000774. Epub 2021 Dec 30. Drug Metab Dispos. 2022. PMID: 34969659

9

¹⁸O-Enabled High-Throughput Acyl Glucuronide Stability Assay.

Yu ZJ, Le H, Tang J, Yue Q, Zhang J, Murray B, Liu X, Smith BJ, Subramanian R. Yu ZJ, et al. Chem Res Toxicol. 2022 Aug 15;35(8):1400-1409. doi: 10.1021/acs.chemrestox.2c00156. Epub 2022 Jul 14. Chem Res Toxicol. 2022. PMID: 35833852

10

Human and nonclinical disposition of [¹⁴C]bictegravir, a potent integrase strand-transfer inhibitor for the treatment of HIV-1 infection.

Subramanian R, Ling J, Wang J, Wang K, Hao J, Jin H, Lai Y, Murray B, Wijaya S, Zhang H, Smith BJ. Subramanian R, et al. Xenobiotica. 2022 Sep-Nov;52(9-11):973-985. doi: 10.1080/00498254.2022.2159569. Epub 2023 Jan 6. Xenobiotica. 2022. PMID: 36546430

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