Xue S - Search Results

1

An enzymatic advance in nicotine cessation therapy.

Xue S , Kallupi M , Zhou B , Smith LC , Miranda PO , George O , Janda KD . Xue S , et al. Chem Commun (Camb). 2018 Feb 13;54(14):1686-1689. doi: 10.1039/c7cc09134f. Chem Commun (Camb). 2018. PMID: 29308799 Free PMC article.

2

A New Strategy for Smoking Cessation: Characterization of a Bacterial Enzyme for the Degradation of Nicotine.

Xue S, Schlosburg JE, Janda KD. Xue S, et al. J Am Chem Soc. 2015 Aug 19;137(32):10136-9. doi: 10.1021/jacs.5b06605. Epub 2015 Aug 6. J Am Chem Soc. 2015. PMID: 26237398

3

An enzymatic approach reverses nicotine dependence, decreases compulsive-like intake, and prevents relapse.

Kallupi M, Xue S, Zhou B, Janda KD, George O. Kallupi M, et al. Among authors: xue s. Sci Adv. 2018 Oct 17;4(10):eaat4751. doi: 10.1126/sciadv.aat4751. eCollection 2018 Oct. Sci Adv. 2018. PMID: 30345354 Free PMC article.

4

Toward the discovery of dual inhibitors for botulinum neurotoxin A: concomitant targeting of endocytosis and light chain protease activity.

Seki H, Xue S, Hixon MS, Pellett S, Remes M, Johnson EA, Janda KD. Seki H, et al. Among authors: xue s. Chem Commun (Camb). 2015 Apr 11;51(28):6226-9. doi: 10.1039/c5cc00677e. Chem Commun (Camb). 2015. PMID: 25759983

5

Picolinic acids as β-exosite inhibitors of botulinum neurotoxin A light chain.

Bremer PT, Xue S, Janda KD. Bremer PT, et al. Among authors: xue s. Chem Commun (Camb). 2016 Oct 13;52(84):12521-12524. doi: 10.1039/c6cc06749b. Chem Commun (Camb). 2016. PMID: 27722252 Free PMC article.

6

Crystallography Coupled with Kinetic Analysis Provides Mechanistic Underpinnings of a Nicotine-Degrading Enzyme.

Tararina MA, Xue S, Smith LC, Muellers SN, Miranda PO, Janda KD, Allen KN. Tararina MA, et al. Among authors: xue s. Biochemistry. 2018 Jul 3;57(26):3741-3751. doi: 10.1021/acs.biochem.8b00384. Epub 2018 Jun 13. Biochemistry. 2018. PMID: 29812904 Free PMC article.

7

Probing BoNT/A protease exosites: implications for inhibitor design and light chain longevity.

Xue S, Javor S, Hixon MS, Janda KD. Xue S, et al. Biochemistry. 2014 Nov 4;53(43):6820-4. doi: 10.1021/bi500950x. Epub 2014 Oct 21. Biochemistry. 2014. PMID: 25295706 Free PMC article.

8

Examination of α-exosite inhibitors against Botulinum neurotoxin A protease through structure-activity relationship studies of chicoric acid.

Xue S, Seki H, Remes M, Šilhár P, Janda K. Xue S, et al. Bioorg Med Chem Lett. 2017 Nov 15;27(22):4956-4959. doi: 10.1016/j.bmcl.2017.10.021. Epub 2017 Oct 12. Bioorg Med Chem Lett. 2017. PMID: 29050781 Free PMC article.

9

Cellular Protection of SNAP-25 against Botulinum Neurotoxin/A: Inhibition of Thioredoxin Reductase through a Suicide Substrate Mechanism.

Seki H, Xue S, Pellett S, Šilhár P, Johnson EA, Janda KD. Seki H, et al. Among authors: xue s. J Am Chem Soc. 2016 May 4;138(17):5568-75. doi: 10.1021/jacs.5b12929. Epub 2016 Apr 20. J Am Chem Soc. 2016. PMID: 27070533 Free PMC article.

10

Phase separation on cell surface facilitates bFGF signal transduction with heparan sulphate.

Xue S, Zhou F, Zhao T, Zhao H, Wang X, Chen L, Li JP, Luo SZ. Xue S, et al. Nat Commun. 2022 Mar 2;13(1):1112. doi: 10.1038/s41467-022-28765-z. Nat Commun. 2022. PMID: 35236856 Free PMC article.

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