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A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial.
Hanratty CE, Matthews JG, Arron JR, Choy DF, Pavord ID, Bradding P, Brightling CE, Chaudhuri R, Cowan DC, Djukanovic R, Gallagher N, Fowler SJ, Hardman TC, Harrison T, Holweg CT, Howarth PH, Lordan J, Mansur AH, Menzies-Gow A, Mosesova S, Niven RM, Robinson DS, Shaw DE, Walker S, Woodcock A, Heaney LG; RASP-UK (Refractory Asthma Stratification Programme) Consortium. Hanratty CE, et al. Among authors: niven rm. Trials. 2018 Jan 4;19(1):5. doi: 10.1186/s13063-017-2384-7. Trials. 2018. PMID: 29301585 Free PMC article.
Composite type-2 biomarker strategy versus a symptom-risk-based algorithm to adjust corticosteroid dose in patients with severe asthma: a multicentre, single-blind, parallel group, randomised controlled trial.
Heaney LG, Busby J, Hanratty CE, Djukanovic R, Woodcock A, Walker SM, Hardman TC, Arron JR, Choy DF, Bradding P, Brightling CE, Chaudhuri R, Cowan DC, Mansur AH, Fowler SJ, Niven RM, Howarth PH, Lordan JL, Menzies-Gow A, Harrison TW, Robinson DS, Holweg CTJ, Matthews JG, Pavord ID; investigators for the MRC Refractory Asthma Stratification Programme. Heaney LG, et al. Among authors: niven rm. Lancet Respir Med. 2021 Jan;9(1):57-68. doi: 10.1016/S2213-2600(20)30397-0. Epub 2020 Sep 8. Lancet Respir Med. 2021. PMID: 32916135 Free PMC article. Clinical Trial.
Factors affecting adherence with treatment advice in a clinical trial of patients with severe asthma.
Busby J, Matthews JG, Chaudhuri R, Pavord ID, Hardman TC, Arron JR, Bradding P, Brightling CE, Choy DF, Cowan DC, Djukanovic R, Hanratty CE, Harrison TW, Holweg CT, Howarth PH, Fowler SJ, Lordan JL, Mansur AH, Menzies-Gow A, Niven RM, Robinson DS, Walker SM, Woodcock A, Heaney LG; investigators for the MRC Refractory Asthma Stratification Programme. Busby J, et al. Among authors: niven rm. Eur Respir J. 2021 Sep 24;59(4):2100768. doi: 10.1183/13993003.00768-2021. Print 2022 Apr. Eur Respir J. 2021. PMID: 34561291 Free PMC article. Clinical Trial.
Using prednisolone and cortisol assays to assess adherence in oral corticosteroid dependant asthma: An analysis of test-retest repeatability.
Busby J, Holweg C, Chai A, Bradding P, Chaudhuri R, Mansur A, Matthews JG, Menzies-Gow A, Lordan J, Niven R, Heaney LG; UK Refractory Asthma Stratification Programme (RASP-UK). Busby J, et al. Pulm Pharmacol Ther. 2020 Oct;64:101951. doi: 10.1016/j.pupt.2020.101951. Epub 2020 Oct 9. Pulm Pharmacol Ther. 2020. PMID: 33045343
Ethnic Differences in Severe Asthma Clinical Care and Outcomes: An Analysis of United Kingdom Primary and Specialist Care.
Busby J, Heaney LG, Brown T, Chaudhuri R, Dennison P, Gore R, Jackson DJ, Mansur AH, Menzies-Gow A, Message S, Niven R, Patel M, Price D, Siddiqui S, Stone R, Pfeffer PE; UK Severe Asthma Registry. Busby J, et al. J Allergy Clin Immunol Pract. 2022 Feb;10(2):495-505.e2. doi: 10.1016/j.jaip.2021.09.034. Epub 2021 Oct 7. J Allergy Clin Immunol Pract. 2022. PMID: 34626858
155 results