Freedman JC - Search Results

1

12-HETrE inhibits platelet reactivity and thrombosis in part through the prostacyclin receptor.

Tourdot BE, Adili R, Isingizwe ZR, Ebrahem M, Freedman JC, Holman TR, Holinstat M. Tourdot BE, et al. Among authors: freedman jc. Blood Adv. 2017 Jun 23;1(15):1124-1131. doi: 10.1182/bloodadvances.2017006155. eCollection 2017 Jun 27. Blood Adv. 2017. PMID: 29296755 Free PMC article.

2

Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency.

Armstrong M, van Hoorebeke C, Horn T, Deschamps J, Freedman JC, Kalyanaraman C, Jacobson MP, Holman T. Armstrong M, et al. Among authors: freedman jc. Bioorg Med Chem. 2016 Nov 1;24(21):5380-5387. doi: 10.1016/j.bmc.2016.08.063. Epub 2016 Aug 31. Bioorg Med Chem. 2016. PMID: 27647374 Free PMC article.

3

First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.

Adili R, Tourdot BE, Mast K, Yeung J, Freedman JC, Green A, Luci DK, Jadhav A, Simeonov A, Maloney DJ, Holman TR, Holinstat M. Adili R, et al. Among authors: freedman jc. Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1828-1839. doi: 10.1161/ATVBAHA.117.309868. Epub 2017 Aug 3. Arterioscler Thromb Vasc Biol. 2017. PMID: 28775075 Free PMC article.

4

15-Lipoxygenase-1 biosynthesis of 7S,14S-diHDHA implicates 15-lipoxygenase-2 in biosynthesis of resolvin D5.

Perry SC, Kalyanaraman C, Tourdot BE, Conrad WS, Akinkugbe O, Freedman JC, Holinstat M, Jacobson MP, Holman TR. Perry SC, et al. Among authors: freedman jc. J Lipid Res. 2020 Jul;61(7):1087-1103. doi: 10.1194/jlr.RA120000777. Epub 2020 May 13. J Lipid Res. 2020. PMID: 32404334 Free PMC article.

5

Supplementation with omega-3 or omega-6 fatty acids attenuates platelet reactivity in postmenopausal women.

Yamaguchi A, Stanger L, Freedman JC, Prieur A, Thav R, Tena J, Holman TR, Holinstat M. Yamaguchi A, et al. Among authors: freedman jc. Clin Transl Sci. 2022 Oct;15(10):2378-2391. doi: 10.1111/cts.13366. Epub 2022 Jul 25. Clin Transl Sci. 2022. PMID: 35791734 Free PMC article.

6

Fatty acids negatively regulate platelet function through formation of noncanonical 15-lipoxygenase-derived eicosanoids.

Yamaguchi A, van Hoorebeke C, Tourdot BE, Perry SC, Lee G, Rhoads N, Rickenberg A, Green AR, Sorrentino J, Yeung J, Freedman JC, Holman TR, Holinstat M. Yamaguchi A, et al. Among authors: freedman jc. Pharmacol Res Perspect. 2023 Feb;11(1):e01056. doi: 10.1002/prp2.1056. Pharmacol Res Perspect. 2023. PMID: 36708179 Free PMC article.

7

Association of Manganese Biomarker Concentrations with Blood Pressure and Kidney Parameters among Healthy Adolescents: NHANES 2013-2018.

Politis MD, Freedman JC, Haynes EN, Sanders AP. Politis MD, et al. Among authors: freedman jc. Children (Basel). 2021 Sep 25;8(10):846. doi: 10.3390/children8100846. Children (Basel). 2021. PMID: 34682111 Free PMC article.

8

Preclinical Evaluation of a Modified Herpes Simplex Virus Type 1 Vector Encoding Human TGM1 for the Treatment of Autosomal Recessive Congenital Ichthyosis.

Freedman JC, Parry TJ, Zhang P, Majumdar A, Krishnan S, Regula LK, O'Malley M, Coghlan S, Yogesha SD, Ramasamy S, Agarwal P. Freedman JC, et al. J Invest Dermatol. 2021 Apr;141(4):874-882.e6. doi: 10.1016/j.jid.2020.07.035. Epub 2020 Sep 22. J Invest Dermatol. 2021. PMID: 32976879 Free article.

9

Identification of an Important Orphan Histidine Kinase for the Initiation of Sporulation and Enterotoxin Production by Clostridium perfringens Type F Strain SM101.

Freedman JC, Li J, Mi E, McClane BA. Freedman JC, et al. mBio. 2019 Jan 22;10(1):e02674-18. doi: 10.1128/mBio.02674-18. mBio. 2019. PMID: 30670619 Free PMC article.

10

Potential Therapeutic Effects of Mepacrine against Clostridium perfringens Enterotoxin in a Mouse Model of Enterotoxemia.

Navarro MA, Shrestha A, Freedman JC, Beingesser J, McClane BA, Uzal FA. Navarro MA, et al. Among authors: freedman jc. Infect Immun. 2019 Mar 25;87(4):e00670-18. doi: 10.1128/IAI.00670-18. Print 2019 Apr. Infect Immun. 2019. PMID: 30642896 Free PMC article.

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