Zou F - Search Results

1

Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening.

Zou F, Pusch S, Hua J, Ma T, Yang L, Zhu Q, Xu Y, Gu Y, von Deimling A, Zha X. Zou F, et al. Bioorg Med Chem Lett. 2018 Feb 1;28(3):388-393. doi: 10.1016/j.bmcl.2017.12.030. Epub 2017 Dec 13. Bioorg Med Chem Lett. 2018. PMID: 29290542

2

Design, synthesis and biological activity of 3-pyrazine-2-yl-oxazolidin-2-ones as novel, potent and selective inhibitors of mutant isocitrate dehydrogenase 1.

Ma T, Zou F, Pusch S, Yang L, Zhu Q, Xu Y, Gu Y, von Deimling A, Zha X. Ma T, et al. Among authors: zou f. Bioorg Med Chem. 2017 Dec 15;25(24):6379-6387. doi: 10.1016/j.bmc.2017.10.009. Epub 2017 Oct 13. Bioorg Med Chem. 2017. PMID: 29089260

3

Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective.

Ma T, Zou F, Pusch S, Xu Y, von Deimling A, Zha X. Ma T, et al. Among authors: zou f. J Med Chem. 2018 Oct 25;61(20):8981-9003. doi: 10.1021/acs.jmedchem.8b00159. Epub 2018 Jun 18. J Med Chem. 2018. PMID: 29847930 Review.

4

Synthesis and analysis of dihydrotetrabenazine derivatives as novel vesicular monoamine transporter 2 inhibitors.

Yang Y, Yu D, Zhu X, Du G, Wang W, Zou F, Wang H, Zhang R, Ye L, Tian J. Yang Y, et al. Among authors: zou f. Eur J Med Chem. 2021 Nov 15;224:113718. doi: 10.1016/j.ejmech.2021.113718. Epub 2021 Jul 24. Eur J Med Chem. 2021. PMID: 34329999

5

Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of PLK1.

Lu J, Lei H, Bai X, Wang W, Liu C, Yang Y, Zou F, Wang L, Wang Y, Du G, Wang X, Sun C, Yu L, Ma M, Ye L, Wang H, Tian J, Zhang J. Lu J, et al. Among authors: zou f. Bioorg Chem. 2023 Oct;139:106711. doi: 10.1016/j.bioorg.2023.106711. Epub 2023 Jul 13. Bioorg Chem. 2023. PMID: 37473479

6

Improving the treatment of Parkinson's disease: Structure-based development of novel 5-HT_2A receptor antagonists/inverse agonists.

Ma M, Yang Y, Du G, Dai Y, Zhu X, Wang W, Xu H, Zhang J, Zheng L, Zou F, Yang H, Liu B, Liu W, Ye L, Zhang R, Tian J. Ma M, et al. Among authors: zou f. Eur J Med Chem. 2022 Apr 15;234:114246. doi: 10.1016/j.ejmech.2022.114246. Epub 2022 Mar 2. Eur J Med Chem. 2022. PMID: 35279606

7

Synthesis and evaluation of piperazinotriazoles. Discovery of a potent and orally bioavailable neurokinin-3 receptor inhibitor.

Ye L, Yang Y, Li C, Zhang J, Wang W, Ma M, Xu H, Zhang W, Zou F, Hu Z, Wang H, Tian J. Ye L, et al. Among authors: zou f. Eur J Med Chem. 2023 Sep 5;257:115486. doi: 10.1016/j.ejmech.2023.115486. Epub 2023 May 13. Eur J Med Chem. 2023. PMID: 37247507

8

PCC0208023, a potent SHP2 allosteric inhibitor, imparts an antitumor effect against KRAS mutant colorectal cancer.

Chen X, Zou F, Hu Z, Du G, Yu P, Wang W, Wang H, Ye L, Tian J. Chen X, et al. Among authors: zou f. Toxicol Appl Pharmacol. 2020 Jul 1;398:115019. doi: 10.1016/j.taap.2020.115019. Epub 2020 Apr 24. Toxicol Appl Pharmacol. 2020. PMID: 32335126

9

Discovery of the thieno[2,3-d]pyrimidine-2,4-dione derivative 21a: A potent and orally bioavailable gonadotropin-releasing hormone receptor antagonist.

Zou F, Wang Y, Yu D, Liu C, Lu J, Zhao M, Ma M, Wang W, Jiang W, Gao Y, Zhang R, Zhang J, Ye L, Tian J. Zou F, et al. Eur J Med Chem. 2022 Nov 15;242:114679. doi: 10.1016/j.ejmech.2022.114679. Epub 2022 Aug 18. Eur J Med Chem. 2022. PMID: 35998545

10

Hi-C Calibration by Chemically Induced Chromosomal Interactions.

Li Y, Zou F, Bai L. Li Y, et al. Among authors: zou f. bioRxiv [Preprint]. 2024 Dec 13:2024.12.09.627644. doi: 10.1101/2024.12.09.627644. bioRxiv. 2024. PMID: 39713426 Free PMC article. Preprint.

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