Gu Y - Search Results

1

Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening.

Zou F, Pusch S, Hua J, Ma T, Yang L, Zhu Q, Xu Y, Gu Y, von Deimling A, Zha X. Zou F, et al. Among authors: gu y. Bioorg Med Chem Lett. 2018 Feb 1;28(3):388-393. doi: 10.1016/j.bmcl.2017.12.030. Epub 2017 Dec 13. Bioorg Med Chem Lett. 2018. PMID: 29290542

2

Pharmacophore modeling and virtual screening for the discovery of new type 4 cAMP phosphodiesterase (PDE4) inhibitors.

Niu M, Dong F, Tang S, Fida G, Qin J, Qiu J, Liu K, Gao W, Gu Y. Niu M, et al. Among authors: gu y. PLoS One. 2013 Dec 10;8(12):e82360. doi: 10.1371/journal.pone.0082360. eCollection 2013. PLoS One. 2013. PMID: 24340020 Free PMC article.

3

New palbociclib analogues modified at the terminal piperazine ring and their anticancer activities.

Wang P, Huang J, Wang K, Gu Y. Wang P, et al. Among authors: gu y. Eur J Med Chem. 2016 Oct 21;122:546-556. doi: 10.1016/j.ejmech.2016.07.020. Epub 2016 Jul 12. Eur J Med Chem. 2016. PMID: 27448913

4

Design, synthesis and biological activity of 3-oxoamino-benzenesulfonamides as selective and reversible LSD1 inhibitors.

Xi J, Xu S, Wu L, Ma T, Liu R, Liu YC, Deng D, Gu Y, Zhou J, Lan F, Zha X. Xi J, et al. Among authors: gu y. Bioorg Chem. 2017 Jun;72:182-189. doi: 10.1016/j.bioorg.2017.04.006. Epub 2017 Apr 13. Bioorg Chem. 2017. PMID: 28460360

5

Design, synthesis and biological activity of 3-pyrazine-2-yl-oxazolidin-2-ones as novel, potent and selective inhibitors of mutant isocitrate dehydrogenase 1.

Ma T, Zou F, Pusch S, Yang L, Zhu Q, Xu Y, Gu Y, von Deimling A, Zha X. Ma T, et al. Among authors: gu y. Bioorg Med Chem. 2017 Dec 15;25(24):6379-6387. doi: 10.1016/j.bmc.2017.10.009. Epub 2017 Oct 13. Bioorg Med Chem. 2017. PMID: 29089260

6

Design, synthesis and biological activity of 4-(4-benzyloxy)phenoxypiperidines as selective and reversible LSD1 inhibitors.

Xi J, Xu S, Zhang L, Bi X, Ren Y, Liu YC, Gu Y, Xu Y, Lan F, Zha X. Xi J, et al. Among authors: gu y. Bioorg Chem. 2018 Aug;78:7-16. doi: 10.1016/j.bioorg.2018.02.016. Epub 2018 Feb 16. Bioorg Chem. 2018. PMID: 29524666

7

A new lysosome-targetable fluorescent probe with a large Stokes shift for detection of endogenous hydrogen polysulfides in living cells.

Ren Y, Zhang L, Zhou Z, Luo Y, Wang S, Yuan S, Gu Y, Xu Y, Zha X. Ren Y, et al. Among authors: gu y. Anal Chim Acta. 2019 May 16;1056:117-124. doi: 10.1016/j.aca.2018.12.051. Epub 2019 Jan 2. Anal Chim Acta. 2019. PMID: 30797452

8

A combination of 2D similarity search, pharmacophore, and molecular docking techniques for the identification of vascular endothelial growth factor receptor-2 inhibitors.

Ai G, Tian C, Deng D, Fida G, Chen H, Ma Y, Ding L, Gu Y. Ai G, et al. Among authors: gu y. Anticancer Drugs. 2015 Apr;26(4):399-409. doi: 10.1097/CAD.0000000000000199. Anticancer Drugs. 2015. PMID: 25569705

9

Novel Linear Peptides with High Affinity to αvβ3 Integrin for Precise Tumor Identification.

Ma Y, Ai G, Zhang C, Zhao M, Dong X, Han Z, Wang Z, Zhang M, Liu Y, Gao W, Li S, Gu Y. Ma Y, et al. Among authors: gu y. Theranostics. 2017 Apr 6;7(6):1511-1523. doi: 10.7150/thno.18401. eCollection 2017. Theranostics. 2017. PMID: 28529634 Free PMC article.

10

Establishment of a screening protocol for identification of aminopeptidase N inhibitors.

Niu M, Wang F, Li F, Dong Y, Gu Y. Niu M, et al. Among authors: gu y. J Taiwan Inst Chem Eng. 2015 Apr;49:19-26. doi: 10.1016/j.jtice.2014.11.028. Epub 2014 Dec 31. J Taiwan Inst Chem Eng. 2015. PMID: 32336998 Free PMC article.

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