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Page 1
Unveiling the role of histidine and tyrosine residues on the conformation of the avian prion hexarepeat domain.
Pietropaolo A, Muccioli L, Zannoni C, La Mendola D, Maccarrone G, Pappalardo G, Rizzarelli E. Pietropaolo A, et al. J Phys Chem B. 2008 Apr 24;112(16):5182-8. doi: 10.1021/jp710702q. Epub 2008 Apr 3. J Phys Chem B. 2008. PMID: 18386869
The prion protein (PrPC) is a glycoprotein that in mammals, differently from avians, can lead to prion diseases, by misfolding into a beta-sheet-rich pathogenic isoform (PrPSc). ...Proteins 2008, 70, 667-677), a conformational dependence on the protonation st …
The prion protein (PrPC) is a glycoprotein that in mammals, differently from avians, can lead to prion diseases, by misfolding into …
Prion proteins leading to neurodegeneration.
La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E. La Mendola D, et al. Among authors: pietropaolo a. Curr Alzheimer Res. 2008 Dec;5(6):579-90. doi: 10.2174/156720508786898415. Curr Alzheimer Res. 2008. PMID: 19075585 Review.
Conformational preferences of the full chicken prion protein in solution and its differences with respect to mammals.
Pietropaolo A, Muccioli L, Zannoni C, Rizzarelli E. Pietropaolo A, et al. Chemphyschem. 2009 Jul 13;10(9-10):1500-10. doi: 10.1002/cphc.200900078. Chemphyschem. 2009. PMID: 19492390
We focus on the persistence of its secondary structure motifs using a recently proposed protein chirality indicator [A. Pietropaolo et al., Proteins 2008, 70, 667-677]. From this, we find a high rigidity of helix 2 (ChPrP178-195) and of the hexarepeat …
We focus on the persistence of its secondary structure motifs using a recently proposed protein chirality indicator [A. Pie …
The inorganic perspectives of neurotrophins and Alzheimer's disease.
Travaglia A, Pietropaolo A, La Mendola D, Nicoletti VG, Rizzarelli E. Travaglia A, et al. Among authors: pietropaolo a. J Inorg Biochem. 2012 Jun;111:130-7. doi: 10.1016/j.jinorgbio.2011.10.017. Epub 2011 Dec 1. J Inorg Biochem. 2012. PMID: 22192858 Review.
238 results