Mo CY - Search Results

1

Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic-Industry Partnership.

Mo CY, Culyba MJ, Selwood T, Kubiak JM, Hostetler ZM, Jurewicz AJ, Keller PM, Pope AJ, Quinn A, Schneck J, Widdowson KL, Kohli RM. Mo CY, et al. ACS Infect Dis. 2018 Mar 9;4(3):349-359. doi: 10.1021/acsinfecdis.7b00122. Epub 2018 Jan 8. ACS Infect Dis. 2018. PMID: 29275629 Free PMC article.

2

Specificity determinants for autoproteolysis of LexA, a key regulator of bacterial SOS mutagenesis.

Mo CY, Birdwell LD, Kohli RM. Mo CY, et al. Biochemistry. 2014 May 20;53(19):3158-68. doi: 10.1021/bi500026e. Epub 2014 May 8. Biochemistry. 2014. PMID: 24779472 Free PMC article.

3

A Small-Molecule Inducible Synthetic Circuit for Control of the SOS Gene Network without DNA Damage.

Kubiak JM, Culyba MJ, Liu MY, Mo CY, Goulian M, Kohli RM. Kubiak JM, et al. Among authors: mo cy. ACS Synth Biol. 2017 Nov 17;6(11):2067-2076. doi: 10.1021/acssynbio.7b00108. Epub 2017 Sep 1. ACS Synth Biol. 2017. PMID: 28826208 Free PMC article.

4

Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network.

Culyba MJ, Kubiak JM, Mo CY, Goulian M, Kohli RM. Culyba MJ, et al. Among authors: mo cy. PLoS Genet. 2018 Jun 1;14(6):e1007405. doi: 10.1371/journal.pgen.1007405. eCollection 2018 Jun. PLoS Genet. 2018. PMID: 29856734 Free PMC article.

5

Targets for Combating the Evolution of Acquired Antibiotic Resistance.

Culyba MJ, Mo CY, Kohli RM. Culyba MJ, et al. Among authors: mo cy. Biochemistry. 2015 Jun 16;54(23):3573-82. doi: 10.1021/acs.biochem.5b00109. Epub 2015 Jun 5. Biochemistry. 2015. PMID: 26016604 Free PMC article. Review.

6

Systematically Altering Bacterial SOS Activity under Stress Reveals Therapeutic Strategies for Potentiating Antibiotics.

Mo CY, Manning SA, Roggiani M, Culyba MJ, Samuels AN, Sniegowski PD, Goulian M, Kohli RM. Mo CY, et al. mSphere. 2016 Aug 10;1(4):e00163-16. doi: 10.1128/mSphere.00163-16. eCollection 2016 Jul-Aug. mSphere. 2016. PMID: 27536734 Free PMC article.

7

Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response.

Selwood T, Larsen BJ, Mo CY, Culyba MJ, Hostetler ZM, Kohli RM, Reitz AB, Baugh SDP. Selwood T, et al. Among authors: mo cy. Front Microbiol. 2018 Dec 18;9:2961. doi: 10.3389/fmicb.2018.02961. eCollection 2018. Front Microbiol. 2018. PMID: 30619111 Free PMC article.

8

High-throughput mutagenesis reveals functional determinants for DNA targeting by activation-induced deaminase.

Gajula KS, Huwe PJ, Mo CY, Crawford DJ, Stivers JT, Radhakrishnan R, Kohli RM. Gajula KS, et al. Among authors: mo cy. Nucleic Acids Res. 2014 Sep;42(15):9964-75. doi: 10.1093/nar/gku689. Epub 2014 Jul 26. Nucleic Acids Res. 2014. PMID: 25064858 Free PMC article.

9

Type III-A CRISPR immunity promotes mutagenesis of staphylococci.

Mo CY, Mathai J, Rostøl JT, Varble A, Banh DV, Marraffini LA. Mo CY, et al. Nature. 2021 Apr;592(7855):611-615. doi: 10.1038/s41586-021-03440-3. Epub 2021 Apr 7. Nature. 2021. PMID: 33828299 Free PMC article.

10

Dynamics of Cas10 Govern Discrimination between Self and Non-self in Type III CRISPR-Cas Immunity.

Wang L, Mo CY, Wasserman MR, Rostøl JT, Marraffini LA, Liu S. Wang L, et al. Among authors: mo cy. Mol Cell. 2019 Jan 17;73(2):278-290.e4. doi: 10.1016/j.molcel.2018.11.008. Epub 2018 Nov 29. Mol Cell. 2019. PMID: 30503774 Free PMC article.

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