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A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice.
Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, Myridakis A, Delzenne NM, Klievink J, Bhattacharjee A, van der Ark KC, Aalvink S, Martinez LO, Dumas ME, Maiter D, Loumaye A, Hermans MP, Thissen JP, Belzer C, de Vos WM, Cani PD. Plovier H, et al. Nat Med. 2017 Jan;23(1):107-113. doi: 10.1038/nm.4236. Epub 2016 Nov 28. Nat Med. 2017. PMID: 27892954 Free article. Clinical Trial.
Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.
Catry E, Bindels LB, Tailleux A, Lestavel S, Neyrinck AM, Goossens JF, Lobysheva I, Plovier H, Essaghir A, Demoulin JB, Bouzin C, Pachikian BD, Cani PD, Staels B, Dessy C, Delzenne NM. Catry E, et al. Among authors: plovier h. Gut. 2018 Feb;67(2):271-283. doi: 10.1136/gutjnl-2016-313316. Epub 2017 Apr 4. Gut. 2018. PMID: 28377388 Free PMC article.
Pasteurized Akkermansia muciniphila protects from fat mass gain but not from bone loss.
Lawenius L, Scheffler JM, Gustafsson KL, Henning P, Nilsson KH, Colldén H, Islander U, Plovier H, Cani PD, de Vos WM, Ohlsson C, Sjögren K. Lawenius L, et al. Among authors: plovier h. Am J Physiol Endocrinol Metab. 2020 Apr 1;318(4):E480-E491. doi: 10.1152/ajpendo.00425.2019. Epub 2020 Jan 21. Am J Physiol Endocrinol Metab. 2020. PMID: 31961709 Free PMC article.
Toxicological safety evaluation of pasteurized Akkermansia muciniphila.
Druart C, Plovier H, Van Hul M, Brient A, Phipps KR, de Vos WM, Cani PD. Druart C, et al. Among authors: plovier h. J Appl Toxicol. 2021 Feb;41(2):276-290. doi: 10.1002/jat.4044. Epub 2020 Jul 28. J Appl Toxicol. 2021. PMID: 32725676 Free PMC article.
Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism.
Duparc T, Plovier H, Marrachelli VG, Van Hul M, Essaghir A, Ståhlman M, Matamoros S, Geurts L, Pardo-Tendero MM, Druart C, Delzenne NM, Demoulin JB, van der Merwe SW, van Pelt J, Bäckhed F, Monleon D, Everard A, Cani PD. Duparc T, et al. Among authors: plovier h. Gut. 2017 Apr;66(4):620-632. doi: 10.1136/gutjnl-2015-310904. Epub 2016 May 5. Gut. 2017. PMID: 27196572 Free PMC article.
23 results