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Design, synthesis, and antiprotozoal evaluation of new 2,9-bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline derivatives.
Guillon J, Cohen A, Das RN, Boudot C, Gueddouda NM, Moreau S, Ronga L, Savrimoutou S, Basmaciyan L, Tisnerat C, Mestanier S, Rubio S, Amaziane S, Dassonville-Klimpt A, Azas N, Courtioux B, Mergny JL, Mullié C, Sonnet P. Guillon J, et al. Among authors: azas n. Chem Biol Drug Des. 2018 May;91(5):974-995. doi: 10.1111/cbdd.13164. Epub 2018 Jan 17. Chem Biol Drug Des. 2018. PMID: 29266861
Synthesis and antiprotozoal activity of 4-arylcoumarins.
Pierson JT, Dumètre A, Hutter S, Delmas F, Laget M, Finet JP, Azas N, Combes S. Pierson JT, et al. Among authors: azas n. Eur J Med Chem. 2010 Mar;45(3):864-9. doi: 10.1016/j.ejmech.2009.10.022. Epub 2009 Oct 23. Eur J Med Chem. 2010. PMID: 19914747
Original quinazoline derivatives displaying antiplasmodial properties.
Kabri Y, Azas N, Dumètre A, Hutter S, Laget M, Verhaeghe P, Gellis A, Vanelle P. Kabri Y, et al. Among authors: azas n. Eur J Med Chem. 2010 Feb;45(2):616-22. doi: 10.1016/j.ejmech.2009.11.005. Epub 2009 Nov 6. Eur J Med Chem. 2010. PMID: 19926173
Targeting the human malaria parasite Plasmodium falciparum: in vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series.
Castera-Ducros C, Azas N, Verhaeghe P, Hutter S, Garrigue P, Dumètre A, Mbatchi L, Laget M, Remusat V, Sifredi F, Rault S, Rathelot P, Vanelle P. Castera-Ducros C, et al. Among authors: azas n. Eur J Med Chem. 2011 Sep;46(9):4184-91. doi: 10.1016/j.ejmech.2011.06.021. Epub 2011 Jun 23. Eur J Med Chem. 2011. PMID: 21741131
4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparum.
Verhaeghe P, Dumètre A, Castera-Ducros C, Hutter S, Laget M, Fersing C, Prieri M, Yzombard J, Sifredi F, Rault S, Rathelot P, Vanelle P, Azas N. Verhaeghe P, et al. Among authors: azas n. Bioorg Med Chem Lett. 2011 Oct 1;21(19):6003-6. doi: 10.1016/j.bmcl.2011.06.113. Epub 2011 Jul 2. Bioorg Med Chem Lett. 2011. PMID: 21852132
97 results