Chan YW - Search Results

1

Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations.

Chan YW, Fugger K, West SC. Chan YW, et al. Nat Cell Biol. 2018 Jan;20(1):92-103. doi: 10.1038/s41556-017-0011-1. Epub 2017 Dec 18. Nat Cell Biol. 2018. PMID: 29255170 Free PMC article.

2

Spatial control of the GEN1 Holliday junction resolvase ensures genome stability.

Chan YW, West SC. Chan YW, et al. Nat Commun. 2014 Sep 11;5:4844. doi: 10.1038/ncomms5844. Nat Commun. 2014. PMID: 25209024 Free PMC article.

3

Resolution of Recombination Intermediates: Mechanisms and Regulation.

West SC, Blanco MG, Chan YW, Matos J, Sarbajna S, Wyatt HD. West SC, et al. Among authors: chan yw. Cold Spring Harb Symp Quant Biol. 2015;80:103-9. doi: 10.1101/sqb.2015.80.027649. Epub 2015 Sep 14. Cold Spring Harb Symp Quant Biol. 2015. PMID: 26370409 Review.

4

GEN1 promotes Holliday junction resolution by a coordinated nick and counter-nick mechanism.

Chan YW, West S. Chan YW, et al. Nucleic Acids Res. 2015 Dec 15;43(22):10882-92. doi: 10.1093/nar/gkv1207. Epub 2015 Nov 17. Nucleic Acids Res. 2015. PMID: 26578604 Free PMC article.

5

Resolution of single and double Holliday junction recombination intermediates by GEN1.

Shah Punatar R, Martin MJ, Wyatt HD, Chan YW, West SC. Shah Punatar R, et al. Among authors: chan yw. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):443-450. doi: 10.1073/pnas.1619790114. Epub 2017 Jan 3. Proc Natl Acad Sci U S A. 2017. PMID: 28049850 Free PMC article.

6

Genome Instability as a Consequence of Defects in the Resolution of Recombination Intermediates.

West SC, Chan YW. West SC, et al. Among authors: chan yw. Cold Spring Harb Symp Quant Biol. 2017;82:207-212. doi: 10.1101/sqb.2017.82.034256. Epub 2018 Jan 18. Cold Spring Harb Symp Quant Biol. 2017. PMID: 29348327

7

GEN1 Endonuclease: Purification and Nuclease Assays.

Chan YW, West SC. Chan YW, et al. Methods Enzymol. 2018;600:527-542. doi: 10.1016/bs.mie.2017.11.020. Epub 2018 Jan 9. Methods Enzymol. 2018. PMID: 29458773

8

A new class of ultrafine anaphase bridges generated by homologous recombination.

Chan YW, West SC. Chan YW, et al. Cell Cycle. 2018;17(17):2101-2109. doi: 10.1080/15384101.2018.1515555. Epub 2018 Sep 25. Cell Cycle. 2018. PMID: 30253678 Free PMC article. Review.

9

GEN1 promotes common fragile site expression.

Benitez A, Sebald M, Kanagaraj R, Rodrigo-Brenni MC, Chan YW, Liang CC, West SC. Benitez A, et al. Among authors: chan yw. Cell Rep. 2023 Feb 28;42(2):112062. doi: 10.1016/j.celrep.2023.112062. Epub 2023 Jan 31. Cell Rep. 2023. PMID: 36729836 Free article.

10

Human Endonuclease ANKLE1 Localizes at the Midbody and Processes Chromatin Bridges to Prevent DNA Damage and cGAS-STING Activation.

Jiang H, Kong N, Liu Z, West SC, Chan YW. Jiang H, et al. Among authors: chan yw. Adv Sci (Weinh). 2023 Apr;10(12):e2204388. doi: 10.1002/advs.202204388. Epub 2023 Feb 24. Adv Sci (Weinh). 2023. PMID: 36825683 Free PMC article.

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