Sciascia T - Search Results

1

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Nalbuphine ER Tablets for Uremic Pruritus.

Mathur VS, Kumar J, Crawford PW, Hait H, Sciascia T; TR02 Study Investigators. Mathur VS, et al. Among authors: sciascia t. Am J Nephrol. 2017;46(6):450-458. doi: 10.1159/000484573. Epub 2017 Dec 18. Am J Nephrol. 2017. PMID: 29253847 Clinical Trial.

2

Pharmacokinetics of nalbuphine hydrochloride extended release tablets in hemodialysis patients with exploratory effect on pruritus.

Hawi A, Alcorn H Jr, Berg J, Hines C, Hait H, Sciascia T. Hawi A, et al. Among authors: sciascia t. BMC Nephrol. 2015 Apr 8;16:47. doi: 10.1186/s12882-015-0043-3. BMC Nephrol. 2015. PMID: 25885112 Free PMC article.

3

Efficacy and safety of oral nalbuphine extended release in prurigo nodularis: results of a phase 2 randomized controlled trial with an open-label extension phase.

Weisshaar E, Szepietowski JC, Bernhard JD, Hait H, Legat FJ, Nattkemper L, Reich A, Sadoghi B, Sciascia TR, Zeidler C, Yosipovitch G, Ständer S. Weisshaar E, et al. Among authors: sciascia tr. J Eur Acad Dermatol Venereol. 2022 Mar;36(3):453-461. doi: 10.1111/jdv.17816. Epub 2021 Dec 1. J Eur Acad Dermatol Venereol. 2022. PMID: 34780095 Clinical Trial.

4

Worst itch numerical rating scale for prurigo nodularis: a psychometric evaluation.

Ständer S, Zeidler C, Pereira M, Szepietowski JC, McLeod L, Qin S, Williams N, Sciascia T, Augustin M. Ständer S, et al. Among authors: sciascia t. J Eur Acad Dermatol Venereol. 2022 Apr;36(4):573-581. doi: 10.1111/jdv.17870. Epub 2022 Feb 14. J Eur Acad Dermatol Venereol. 2022. PMID: 34908192 Clinical Trial.

5

A population pharmacokinetic-pharmacodynamic model evaluating efficacy of nalbuphine extended-release in patients with prurigo nodularis.

Eudy-Byrne R, Riggs M, Hawi A, Sciascia T, Rohatagi S. Eudy-Byrne R, et al. Among authors: sciascia t. Br J Clin Pharmacol. 2023 Jul;89(7):2088-2101. doi: 10.1111/bcp.15663. Epub 2023 Feb 9. Br J Clin Pharmacol. 2023. PMID: 36680419 Free article.

6

Disposition of Oral Nalbuphine and Its Metabolites in Healthy Subjects and Subjects with Hepatic Impairment: Preliminary Modeling Results Using a Continuous Intestinal Absorption Model with Enterohepatic Recirculation.

Nagar S, Hawi A, Sciascia T, Korzekwa K. Nagar S, et al. Among authors: sciascia t. Metabolites. 2024 Aug 27;14(9):471. doi: 10.3390/metabo14090471. Metabolites. 2024. PMID: 39330478 Free PMC article.

7

Modulation of the kappa and mu opioid axis for the treatment of chronic pruritus: A review of basic science and clinical implications.

Elmariah S, Chisolm S, Sciascia T, Kwatra SG. Elmariah S, et al. Among authors: sciascia t. JAAD Int. 2022 Apr 20;7:156-163. doi: 10.1016/j.jdin.2022.03.007. eCollection 2022 Jun. JAAD Int. 2022. PMID: 35497636 Free PMC article.

8

A Continuous Intestinal Absorption Model to Predict Drug Enterohepatic Recirculation in Healthy Humans: Nalbuphine as a Model Substrate.

Korzekwa K, Nagar S, Clark D, Sciascia T, Hawi A. Korzekwa K, et al. Among authors: sciascia t. Mol Pharm. 2024 Sep 2;21(9):4510-4523. doi: 10.1021/acs.molpharmaceut.4c00424. Epub 2024 Jul 2. Mol Pharm. 2024. PMID: 38956965

9

Use of an adaptive study design in single ascending-dose pharmacokinetics of A0001 (α-tocopherylquinone) in healthy male subjects.

Hawi A, Heald S, Sciascia T. Hawi A, et al. Among authors: sciascia t. J Clin Pharmacol. 2012 Jan;52(1):65-77. doi: 10.1177/0091270010390807. Epub 2011 Feb 22. J Clin Pharmacol. 2012. PMID: 21343342 Clinical Trial.

10

A0001 in Friedreich ataxia: biochemical characterization and effects in a clinical trial.

Lynch DR, Willi SM, Wilson RB, Cotticelli MG, Brigatti KW, Deutsch EC, Kucheruk O, Shrader W, Rioux P, Miller G, Hawi A, Sciascia T. Lynch DR, et al. Among authors: sciascia t. Mov Disord. 2012 Jul;27(8):1026-33. doi: 10.1002/mds.25058. Epub 2012 Jun 28. Mov Disord. 2012. PMID: 22744651 Clinical Trial.

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