Weiner D - Search Results

1

Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer.

Veglia F, Tyurin VA, Mohammadyani D, Blasi M, Duperret EK, Donthireddy L, Hashimoto A, Kapralov A, Amoscato A, Angelini R, Patel S, Alicea-Torres K, Weiner D, Murphy ME, Klein-Seetharaman J, Celis E, Kagan VE, Gabrilovich DI. Veglia F, et al. Among authors: weiner d. Nat Commun. 2017 Dec 14;8(1):2122. doi: 10.1038/s41467-017-02186-9. Nat Commun. 2017. PMID: 29242535 Free PMC article.

2

A Novel DNA Vaccine Platform Enhances Neo-antigen-like T Cell Responses against WT1 to Break Tolerance and Induce Anti-tumor Immunity.

Walters JN, Ferraro B, Duperret EK, Kraynyak KA, Chu J, Saint-Fleur A, Yan J, Levitsky H, Khan AS, Sardesai NY, Weiner DB. Walters JN, et al. Mol Ther. 2017 Apr 5;25(4):976-988. doi: 10.1016/j.ymthe.2017.01.022. Epub 2017 Feb 22. Mol Ther. 2017. PMID: 28237837 Free PMC article.

3

Novel prostate cancer immunotherapy with a DNA-encoded anti-prostate-specific membrane antigen monoclonal antibody.

Muthumani K, Marnin L, Kudchodkar SB, Perales-Puchalt A, Choi H, Agarwal S, Scott VL, Reuschel EL, Zaidi FI, Duperret EK, Wise MC, Kraynyak KA, Ugen KE, Sardesai NY, Joseph Kim J, Weiner DB. Muthumani K, et al. Cancer Immunol Immunother. 2017 Dec;66(12):1577-1588. doi: 10.1007/s00262-017-2042-7. Epub 2017 Aug 17. Cancer Immunol Immunother. 2017. PMID: 28819703 Free PMC article.

4

An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model.

Patel A, DiGiandomenico A, Keller AE, Smith TRF, Park DH, Ramos S, Schultheis K, Elliott STC, Mendoza J, Broderick KE, Wise MC, Yan J, Jiang J, Flingai S, Khan AS, Muthumani K, Humeau L, Cheng LI, Wachter-Rosati L, Stover CK, Sardesai NY, Weiner DB. Patel A, et al. Nat Commun. 2017 Sep 21;8(1):637. doi: 10.1038/s41467-017-00576-7. Nat Commun. 2017. PMID: 28935938 Free PMC article.

5

Synergy of Immune Checkpoint Blockade with a Novel Synthetic Consensus DNA Vaccine Targeting TERT.

Duperret EK, Wise MC, Trautz A, Villarreal DO, Ferraro B, Walters J, Yan J, Khan A, Masteller E, Humeau L, Weiner DB. Duperret EK, et al. Mol Ther. 2018 Feb 7;26(2):435-445. doi: 10.1016/j.ymthe.2017.11.010. Epub 2017 Nov 21. Mol Ther. 2018. PMID: 29249395 Free PMC article.

6

Alteration of the Tumor Stroma Using a Consensus DNA Vaccine Targeting Fibroblast Activation Protein (FAP) Synergizes with Antitumor Vaccine Therapy in Mice.

Duperret EK, Trautz A, Ammons D, Perales-Puchalt A, Wise MC, Yan J, Reed C, Weiner DB. Duperret EK, et al. Among authors: weiner db. Clin Cancer Res. 2018 Mar 1;24(5):1190-1201. doi: 10.1158/1078-0432.CCR-17-2033. Epub 2017 Dec 21. Clin Cancer Res. 2018. PMID: 29269377 Free PMC article.

7

A Designer Cross-reactive DNA Immunotherapeutic Vaccine that Targets Multiple MAGE-A Family Members Simultaneously for Cancer Therapy.

Duperret EK, Liu S, Paik M, Trautz A, Stoltz R, Liu X, Ze K, Perales-Puchalt A, Reed C, Yan J, Xu X, Weiner DB. Duperret EK, et al. Clin Cancer Res. 2018 Dec 1;24(23):6015-6027. doi: 10.1158/1078-0432.CCR-18-1013. Epub 2018 Sep 27. Clin Cancer Res. 2018. PMID: 30262507 Free PMC article.

8

Synthetic DNA-Encoded Monoclonal Antibody Delivery of Anti-CTLA-4 Antibodies Induces Tumor Shrinkage In Vivo.

Duperret EK, Trautz A, Stoltz R, Patel A, Wise MC, Perales-Puchalt A, Smith T, Broderick KE, Masteller E, Kim JJ, Humeau L, Muthumani K, Weiner DB. Duperret EK, et al. Cancer Res. 2018 Nov 15;78(22):6363-6370. doi: 10.1158/0008-5472.CAN-18-1429. Epub 2018 Oct 4. Cancer Res. 2018. PMID: 30287678 Free PMC article.

9

Designing consensus immunogens to break tolerance to self-antigens for cancer therapy.

Duperret EK, Yan J, Weiner DB. Duperret EK, et al. Oncotarget. 2018 Oct 30;9(85):35513-35514. doi: 10.18632/oncotarget.26275. eCollection 2018 Oct 30. Oncotarget. 2018. PMID: 30473745 Free PMC article. No abstract available.

10

IL-33 delays metastatic peritoneal cancer progression inducing an allergic microenvironment.

Perales-Puchalt A, Svoronos N, Villarreal DO, Zankharia U, Reuschel E, Wojtak K, Payne KK, Duperret EK, Muthumani K, Conejo-Garcia JR, Weiner DB. Perales-Puchalt A, et al. Oncoimmunology. 2018 Sep 6;8(1):e1515058. doi: 10.1080/2162402X.2018.1515058. eCollection 2019. Oncoimmunology. 2018. PMID: 30546956 Free PMC article.

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