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Page 1
Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer.
Veglia F, Tyurin VA, Mohammadyani D, Blasi M, Duperret EK, Donthireddy L, Hashimoto A, Kapralov A, Amoscato A, Angelini R, Patel S, Alicea-Torres K, Weiner D, Murphy ME, Klein-Seetharaman J, Celis E, Kagan VE, Gabrilovich DI. Veglia F, et al. Among authors: kapralov a. Nat Commun. 2017 Dec 14;8(1):2122. doi: 10.1038/s41467-017-02186-9. Nat Commun. 2017. PMID: 29242535 Free PMC article.
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium.
Dar HH, Tyurina YY, Mikulska-Ruminska K, Shrivastava I, Ting HC, Tyurin VA, Krieger J, St Croix CM, Watkins S, Bayir E, Mao G, Armbruster CR, Kapralov A, Wang H, Parsek MR, Anthonymuthu TS, Ogunsola AF, Flitter BA, Freedman CJ, Gaston JR, Holman TR, Pilewski JM, Greenberger JS, Mallampalli RK, Doi Y, Lee JS, Bahar I, Bomberger JM, Bayır H, Kagan VE. Dar HH, et al. Among authors: kapralov a. J Clin Invest. 2018 Oct 1;128(10):4639-4653. doi: 10.1172/JCI99490. Epub 2018 Sep 10. J Clin Invest. 2018. PMID: 30198910 Free PMC article.
Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells.
Godoy LC, Muñoz-Pinedo C, Castro L, Cardaci S, Schonhoff CM, King M, Tórtora V, Marín M, Miao Q, Jiang JF, Kapralov A, Jemmerson R, Silkstone GG, Patel JN, Evans JE, Wilson MT, Green DR, Kagan VE, Radi R, Mannick JB. Godoy LC, et al. Among authors: kapralov a. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2653-8. doi: 10.1073/pnas.0809279106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196960 Free PMC article.
Compartmentalized mitochondrial ferroptosis converges with optineurin-mediated mitophagy to impact airway epithelial cell phenotypes and asthma outcomes.
Yamada K, St Croix C, Stolz DB, Tyurina YY, Tyurin VA, Bradley LR, Kapralov AA, Deng Y, Zhou X, Wei Q, Liao B, Fukuda N, Sullivan M, Trudeau J, Ray A, Kagan VE, Zhao J, Wenzel SE. Yamada K, et al. Among authors: kapralov aa. Nat Commun. 2024 Jul 10;15(1):5818. doi: 10.1038/s41467-024-50222-2. Nat Commun. 2024. PMID: 38987265 Free PMC article.
PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression.
Yang X, Wang Z, Samovich SN, Kapralov AA, Amoscato AA, Tyurin VA, Dar HH, Li Z, Duan S, Kon N, Chen D, Tycko B, Zhang Z, Jiang X, Bayir H, Stockwell BR, Kagan VE, Gu W. Yang X, et al. Among authors: kapralov aa. Cell Metab. 2024 Apr 2;36(4):762-777.e9. doi: 10.1016/j.cmet.2024.01.006. Epub 2024 Feb 2. Cell Metab. 2024. PMID: 38309267 Free PMC article.
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death.
Samovich SN, Mikulska-Ruminska K, Dar HH, Tyurina YY, Tyurin VA, Souryavong AB, Kapralov AA, Amoscato AA, Beharier O, Karumanchi SA, St Croix CM, Yang X, Holman TR, VanDemark AP, Sadovsky Y, Mallampalli RK, Wenzel SE, Gu W, Bunimovich YL, Bahar I, Kagan VE, Bayir H. Samovich SN, et al. Among authors: kapralov aa. Angew Chem Int Ed Engl. 2024 Feb 26;63(9):e202314710. doi: 10.1002/anie.202314710. Epub 2024 Jan 17. Angew Chem Int Ed Engl. 2024. PMID: 38230815
89 results