Pavletich NP - Search Results

1

Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.

Yang H, Jiang X, Li B, Yang HJ, Miller M, Yang A, Dhar A, Pavletich NP. Yang H, et al. Among authors: pavletich np. Nature. 2017 Dec 21;552(7685):368-373. doi: 10.1038/nature25023. Epub 2017 Dec 13. Nature. 2017. PMID: 29236692 Free PMC article.

2

Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.

Chen Z, Yang H, Pavletich NP. Chen Z, et al. Among authors: pavletich np. Nature. 2008 May 22;453(7194):489-4. doi: 10.1038/nature06971. Nature. 2008. PMID: 18497818

3

mTOR kinase structure, mechanism and regulation.

Yang H, Rudge DG, Koos JD, Vaidialingam B, Yang HJ, Pavletich NP. Yang H, et al. Among authors: pavletich np. Nature. 2013 May 9;497(7448):217-23. doi: 10.1038/nature12122. Epub 2013 May 1. Nature. 2013. PMID: 23636326 Free PMC article.

4

DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.

Wang R, Wang S, Dhar A, Peralta C, Pavletich NP. Wang R, et al. Among authors: pavletich np. Nature. 2020 Apr;580(7802):278-282. doi: 10.1038/s41586-020-2110-6. Epub 2020 Mar 11. Nature. 2020. PMID: 32269332 Free PMC article.

5

Mechanism of strand exchange from RecA-DNA synaptic and D-loop structures.

Yang H, Zhou C, Dhar A, Pavletich NP. Yang H, et al. Among authors: pavletich np. Nature. 2020 Oct;586(7831):801-806. doi: 10.1038/s41586-020-2820-9. Epub 2020 Oct 14. Nature. 2020. PMID: 33057191 Free PMC article.

6

The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction.

Yang H, Li Q, Fan J, Holloman WK, Pavletich NP. Yang H, et al. Among authors: pavletich np. Nature. 2005 Feb 10;433(7026):653-7. doi: 10.1038/nature03234. Nature. 2005. PMID: 15703751

7

Insights into homology search from cryo-EM structures of RecA-DNA recombination intermediates.

Yang H, Pavletich NP. Yang H, et al. Among authors: pavletich np. Curr Opin Genet Dev. 2021 Dec;71:188-194. doi: 10.1016/j.gde.2021.09.002. Epub 2021 Sep 27. Curr Opin Genet Dev. 2021. PMID: 34592688 Free PMC article. Review.

8

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.

Yang H, Jeffrey PD, Miller J, Kinnucan E, Sun Y, Thoma NH, Zheng N, Chen PL, Lee WH, Pavletich NP. Yang H, et al. Among authors: pavletich np. Science. 2002 Sep 13;297(5588):1837-48. doi: 10.1126/science.297.5588.1837. Science. 2002. PMID: 12228710

9

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.

Russo AA, Jeffrey PD, Patten AK, Massagué J, Pavletich NP. Russo AA, et al. Among authors: pavletich np. Nature. 1996 Jul 25;382(6589):325-31. doi: 10.1038/382325a0. Nature. 1996. PMID: 8684460

10

Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.

Russo AA, Tong L, Lee JO, Jeffrey PD, Pavletich NP. Russo AA, et al. Among authors: pavletich np. Nature. 1998 Sep 17;395(6699):237-43. doi: 10.1038/26155. Nature. 1998. PMID: 9751050

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