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Phytochemical study and evaluation of cytotoxicity, mutagenicity, cell cycle kinetics and gene expression of Bauhinia holophylla (Bong.) Steud. in HepG2 cells in vitro.
Ribeiro DL, Cilião HL, Specian AFL, Serpeloni JM, De Oliveira MT, Varanda EA, Vilegas W, Saldanha LL, Martínez-López W, Dokkedal AL, Cólus IMS. Ribeiro DL, et al. Among authors: specian afl. Cytotechnology. 2018 Apr;70(2):713-728. doi: 10.1007/s10616-017-0173-5. Epub 2017 Dec 11. Cytotechnology. 2018. PMID: 29230630 Free PMC article.
Chemical and biological characterisation of Machaerium hirtum (Vell.) Stellfeld: absence of cytotoxicity and mutagenicity and possible chemopreventive potential.
Ribeiro DL, Cilião HL, Specian AF, Serpeloni JM, de Souza MF, Tangerina MM, Vilegas W, Boldrin PK, Resende FA, Varanda EA, Martínez-López W, Sannomiya M, Cólus IM. Ribeiro DL, et al. Mutagenesis. 2016 Mar;31(2):147-60. doi: 10.1093/mutage/gev066. Epub 2015 Aug 27. Mutagenesis. 2016. PMID: 26314304
Chemical characterization of Brazilian savannah Byrsonima species (muricis) and their impact on genomic instability and chemopreventive effects.
Specian AFL, Tuttis K, Serpeloni JM, Ribeiro DL, Nunes HL, Tangerina MMP, Sannomiya M, Varanda EA, Vilegas W, Cólus IMS. Specian AFL, et al. Mutat Res Genet Toxicol Environ Mutagen. 2023 Apr;887:503586. doi: 10.1016/j.mrgentox.2023.503586. Epub 2023 Jan 18. Mutat Res Genet Toxicol Environ Mutagen. 2023. PMID: 37003647
Fridericia platyphylla (Cham.) L.G. Lohmann root extract exerts cytotoxic and antiproliferative effects on gastric tumor cells and downregulates BCL-XL, BIRC5, and MET genes.
Serpeloni JM, Specian A, Ribeiro DL, Benício LM, Nunes HL, Franchi LP, Rocha CQ, Vilegas W, Varanda EA, Cólus I. Serpeloni JM, et al. Among authors: specian a. Hum Exp Toxicol. 2020 Mar;39(3):338-354. doi: 10.1177/0960327119888261. Epub 2019 Nov 14. Hum Exp Toxicol. 2020. PMID: 31726875