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A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models.
Zhou Y, Castonguay P, Sidhom EH, Clark AR, Dvela-Levitt M, Kim S, Sieber J, Wieder N, Jung JY, Andreeva S, Reichardt J, Dubois F, Hoffmann SC, Basgen JM, Montesinos MS, Weins A, Johnson AC, Lander ES, Garrett MR, Hopkins CR, Greka A. Zhou Y, et al. Science. 2017 Dec 8;358(6368):1332-1336. doi: 10.1126/science.aal4178. Science. 2017. PMID: 29217578 Free PMC article.
Calcium-permeable ion channels in the kidney.
Zhou Y, Greka A. Zhou Y, et al. Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1157-67. doi: 10.1152/ajprenal.00117.2016. Epub 2016 Mar 30. Am J Physiol Renal Physiol. 2016. PMID: 27029425 Free PMC article. Review.
Structures and gating mechanism of human TRPM2.
Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Wang L, et al. Among authors: zhou y. Science. 2018 Dec 21;362(6421):eaav4809. doi: 10.1126/science.aav4809. Epub 2018 Nov 22. Science. 2018. PMID: 30467180 Free PMC article.
Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation.
Subramanian A, Sidhom EH, Emani M, Vernon K, Sahakian N, Zhou Y, Kost-Alimova M, Slyper M, Waldman J, Dionne D, Nguyen LT, Weins A, Marshall JL, Rosenblatt-Rosen O, Regev A, Greka A. Subramanian A, et al. Among authors: zhou y. Nat Commun. 2019 Nov 29;10(1):5462. doi: 10.1038/s41467-019-13382-0. Nat Commun. 2019. PMID: 31784515 Free PMC article.
Protective role for kidney TREM2high macrophages in obesity- and diabetes-induced kidney injury.
Subramanian A, Vernon KA, Zhou Y, Marshall JL, Alimova M, Arevalo C, Zhang F, Slyper M, Waldman J, Montesinos MS, Dionne D, Nguyen LT, Cuoco MS, Dubinsky D, Purnell J, Keller K, Sturner SH, Grinkevich E, Ghoshal A, Kotek A, Trivioli G, Richoz N, Humphrey MB, Darby IG, Miller SJ, Xu Y, Weins A, Chloe-Villani A, Chang SL, Kretzler M, Rosenblatt-Rosen O, Shaw JL, Zimmerman KA, Clatworthy MR, Regev A, Greka A. Subramanian A, et al. Among authors: zhou y. Cell Rep. 2024 Jun 25;43(6):114253. doi: 10.1016/j.celrep.2024.114253. Epub 2024 May 22. Cell Rep. 2024. PMID: 38781074 Free PMC article.
Diagnosis and treatment recommendations for glucose transporter 1 deficiency syndrome.
Zhang MJ, Wu D, Yu LF, Li H, Sun D, Liang JM, Lu XP, Luo R, Guo QH, Jin RF, Zhang HW, Lei GF, Sun RP, Wang M, Zhou YF, Wang YY, Tang JH, Hua Y, Shi XL, Liu XM, Shi XY, Yang G, Wang H, Gao F, Jia TM, Wang JW, Liao JX, Bao XH. Zhang MJ, et al. Among authors: zhou yf. World J Pediatr. 2025 Jan 2. doi: 10.1007/s12519-024-00864-5. Online ahead of print. World J Pediatr. 2025. PMID: 39745620 Review.
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