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Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species.
Muttenthaler M, Andersson Å, Vetter I, Menon R, Busnelli M, Ragnarsson L, Bergmayr C, Arrowsmith S, Deuis JR, Chiu HS, Palpant NJ, O'Brien M, Smith TJ, Wray S, Neumann ID, Gruber CW, Lewis RJ, Alewood PF. Muttenthaler M, et al. Among authors: wray s. Sci Signal. 2017 Dec 5;10(508):eaan3398. doi: 10.1126/scisignal.aan3398. Sci Signal. 2017. PMID: 29208680 Free PMC article.
What do we know about what happens to myometrial function as women age?
Arrowsmith S, Robinson H, Noble K, Wray S. Arrowsmith S, et al. Among authors: wray s. J Muscle Res Cell Motil. 2012 Aug;33(3-4):209-17. doi: 10.1007/s10974-012-9300-2. Epub 2012 May 30. J Muscle Res Cell Motil. 2012. PMID: 22644420 Free PMC article.
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.
Koehbach J, O'Brien M, Muttenthaler M, Miazzo M, Akcan M, Elliott AG, Daly NL, Harvey PJ, Arrowsmith S, Gunasekera S, Smith TJ, Wray S, Göransson U, Dawson PE, Craik DJ, Freissmuth M, Gruber CW. Koehbach J, et al. Among authors: wray s. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21183-8. doi: 10.1073/pnas.1311183110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248349 Free PMC article.
Myometrial physiology--time to translate?
Arrowsmith S, Kendrick A, Hanley JA, Noble K, Wray S. Arrowsmith S, et al. Among authors: wray s. Exp Physiol. 2014 Mar;99(3):495-502. doi: 10.1113/expphysiol.2013.076216. Epub 2013 Dec 6. Exp Physiol. 2014. PMID: 24317408 Free article. Review.
Drugs acting on the pregnant uterus.
Arrowsmith S, Kendrick A, Wray S. Arrowsmith S, et al. Among authors: wray s. Obstet Gynaecol Reprod Med. 2010 Aug;20(8):241-247. doi: 10.1016/j.ogrm.2010.05.001. Obstet Gynaecol Reprod Med. 2010. PMID: 24443652 Free PMC article.
650 results