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Page 1
Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species.
Muttenthaler M, Andersson Å, Vetter I, Menon R, Busnelli M, Ragnarsson L, Bergmayr C, Arrowsmith S, Deuis JR, Chiu HS, Palpant NJ, O'Brien M, Smith TJ, Wray S, Neumann ID, Gruber CW, Lewis RJ, Alewood PF. Muttenthaler M, et al. Among authors: palpant nj. Sci Signal. 2017 Dec 5;10(508):eaan3398. doi: 10.1126/scisignal.aan3398. Sci Signal. 2017. PMID: 29208680 Free PMC article.
Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias.
Selvakumar D, Clayton ZE, Prowse A, Dingwall S, Kim SK, Reyes L, George J, Shah H, Chen S, Leung HHL, Hume RD, Tjahjadi L, Igoor S, Skelton RJP, Hing A, Paterson H, Foster SL, Pearson L, Wilkie E, Marcus AD, Jeyaprakash P, Wu Z, Chiu HS, Ongtengco CFJ, Mulay O, McArthur JR, Barry T, Lu J, Tran V, Bennett R, Kotake Y, Campbell T, Turnbull S, Gupta A, Nguyen Q, Ni G, Grieve SM, Palpant NJ, Pathan F, Kizana E, Kumar S, Gray PP, Chong JJH. Selvakumar D, et al. Among authors: palpant nj. Nat Cardiovasc Res. 2024 Feb;3(2):145-165. doi: 10.1038/s44161-023-00419-3. Epub 2024 Feb 6. Nat Cardiovasc Res. 2024. PMID: 39196193 Free PMC article.
Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function.
Sinclair JE, Vedelago C, Ryan FJ, Carney M, Redd MA, Lynn MA, Grubor-Bauk B, Cao Y, Henders AK, Chew KY, Gilroy D, Greaves K, Labzin L, Ziser L, Ronacher K, Wallace LM, Zhang Y, Macauslane K, Ellis DJ, Rao S, Burr L, Bain A, Karawita A, Schulz BL, Li J, Lynn DJ, Palpant N, Wuethrich A, Trau M, Short KR. Sinclair JE, et al. Nat Microbiol. 2024 Dec;9(12):3135-3147. doi: 10.1038/s41564-024-01838-z. Epub 2024 Oct 30. Nat Microbiol. 2024. PMID: 39478108 Free PMC article.
Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation.
Friedman CE, Nguyen Q, Lukowski SW, Helfer A, Chiu HS, Miklas J, Levy S, Suo S, Han JJ, Osteil P, Peng G, Jing N, Baillie GJ, Senabouth A, Christ AN, Bruxner TJ, Murry CE, Wong ES, Ding J, Wang Y, Hudson J, Ruohola-Baker H, Bar-Joseph Z, Tam PPL, Powell JE, Palpant NJ. Friedman CE, et al. Among authors: palpant nj. Cell Stem Cell. 2018 Oct 4;23(4):586-598.e8. doi: 10.1016/j.stem.2018.09.009. Cell Stem Cell. 2018. PMID: 30290179 Free PMC article.
Genotype-free demultiplexing of pooled single-cell RNA-seq.
Xu J, Falconer C, Nguyen Q, Crawford J, McKinnon BD, Mortlock S, Senabouth A, Andersen S, Chiu HS, Jiang L, Palpant NJ, Yang J, Mueller MD, Hewitt AW, Pébay A, Montgomery GW, Powell JE, Coin LJM. Xu J, et al. Among authors: palpant nj. Genome Biol. 2019 Dec 19;20(1):290. doi: 10.1186/s13059-019-1852-7. Genome Biol. 2019. PMID: 31856883 Free PMC article.
Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells.
Neavin D, Nguyen Q, Daniszewski MS, Liang HH, Chiu HS, Wee YK, Senabouth A, Lukowski SW, Crombie DE, Lidgerwood GE, Hernández D, Vickers JC, Cook AL, Palpant NJ, Pébay A, Hewitt AW, Powell JE. Neavin D, et al. Among authors: palpant nj. Genome Biol. 2021 Mar 5;22(1):76. doi: 10.1186/s13059-021-02293-3. Genome Biol. 2021. PMID: 33673841 Free PMC article.
Therapeutic Inhibition of Acid-Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury.
Redd MA, Scheuer SE, Saez NJ, Yoshikawa Y, Chiu HS, Gao L, Hicks M, Villanueva JE, Joshi Y, Chow CY, Cuellar-Partida G, Peart JN, See Hoe LE, Chen X, Sun Y, Suen JY, Hatch RJ, Rollo B, Xia D, Alzubaidi MAH, Maljevic S, Quaife-Ryan GA, Hudson JE, Porrello ER, White MY, Cordwell SJ, Fraser JF, Petrou S, Reichelt ME, Thomas WG, King GF, Macdonald PS, Palpant NJ. Redd MA, et al. Among authors: palpant nj. Circulation. 2021 Sep 21;144(12):947-960. doi: 10.1161/CIRCULATIONAHA.121.054360. Epub 2021 Jul 15. Circulation. 2021. PMID: 34264749 Free article.
64 results