Kumar A - Search Results

1

Understanding the extracellular forces that determine cell fate and maintenance.

Kumar A, Placone JK, Engler AJ. Kumar A, et al. Development. 2017 Dec 1;144(23):4261-4270. doi: 10.1242/dev.158469. Development. 2017. PMID: 29183939 Free PMC article. Review.

2

Mechanical regulation of cardiac fibroblast profibrotic phenotypes.

Herum KM, Choppe J, Kumar A, Engler AJ, McCulloch AD. Herum KM, et al. Among authors: kumar a. Mol Biol Cell. 2017 Jul 7;28(14):1871-1882. doi: 10.1091/mbc.E17-01-0014. Epub 2017 May 3. Mol Biol Cell. 2017. PMID: 28468977 Free PMC article.

3

RAP2 mediates mechanoresponses of the Hippo pathway.

Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL. Meng Z, et al. Among authors: kumar a. Nature. 2018 Aug;560(7720):655-660. doi: 10.1038/s41586-018-0444-0. Epub 2018 Aug 22. Nature. 2018. PMID: 30135582 Free PMC article.

4

Macromolecular crowding tunes 3D collagen architecture and cell morphogenesis.

Ranamukhaarachchi SK , Modi RN , Han A , Velez DO , Kumar A , Engler AJ , Fraley SI . Ranamukhaarachchi SK , et al. Among authors: kumar a. Biomater Sci. 2019 Jan 29;7(2):618-633. doi: 10.1039/c8bm01188e. Biomater Sci. 2019. PMID: 30515503 Free PMC article.

5

Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing.

Lo Sardo V, Chubukov P, Ferguson W, Kumar A, Teng EL, Duran M, Zhang L, Cost G, Engler AJ, Urnov F, Topol EJ, Torkamani A, Baldwin KK. Lo Sardo V, et al. Among authors: kumar a. Cell. 2018 Dec 13;175(7):1796-1810.e20. doi: 10.1016/j.cell.2018.11.014. Epub 2018 Dec 6. Cell. 2018. PMID: 30528432 Free PMC article.

6

Matrix stiffness mechanically conditions EMT and migratory behavior of oral squamous cell carcinoma.

Matte BF, Kumar A, Placone JK, Zanella VG, Martins MD, Engler AJ, Lamers ML. Matte BF, et al. Among authors: kumar a. J Cell Sci. 2019 Jan 9;132(1):jcs224360. doi: 10.1242/jcs.224360. J Cell Sci. 2019. PMID: 30559248 Free PMC article.

7

Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling.

Ondeck MG, Kumar A, Placone JK, Plunkett CM, Matte BF, Wong KC, Fattet L, Yang J, Engler AJ. Ondeck MG, et al. Among authors: kumar a. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3502-3507. doi: 10.1073/pnas.1814204116. Epub 2019 Feb 12. Proc Natl Acad Sci U S A. 2019. PMID: 30755531 Free PMC article.

8

Mechanical activation of noncoding-RNA-mediated regulation of disease-associated phenotypes in human cardiomyocytes.

Kumar A, Thomas SK, Wong KC, Lo Sardo V, Cheah DS, Hou YH, Placone JK, Tenerelli KP, Ferguson WC, Torkamani A, Topol EJ, Baldwin KK, Engler AJ. Kumar A, et al. Nat Biomed Eng. 2019 Feb;3(2):137-146. doi: 10.1038/s41551-018-0344-5. Epub 2019 Jan 28. Nat Biomed Eng. 2019. PMID: 30911429 Free PMC article.

9

3D collagen architecture regulates cell adhesion through degradability, thereby controlling metabolic and oxidative stress.

Velez DO, Ranamukhaarachchi SK, Kumar A, Modi RN, Lim EW, Engler AJ, Metallo CM, Fraley SI. Velez DO, et al. Among authors: kumar a. Integr Biol (Camb). 2019 May 1;11(5):221-234. doi: 10.1093/intbio/zyz019. Integr Biol (Camb). 2019. PMID: 31251330 Free PMC article.

10

Cell Adhesiveness Serves as a Biophysical Marker for Metastatic Potential.

Beri P, Popravko A, Yeoman B, Kumar A, Chen K, Hodzic E, Chiang A, Banisadr A, Placone JK, Carter H, Fraley SI, Katira P, Engler AJ. Beri P, et al. Among authors: kumar a. Cancer Res. 2020 Feb 15;80(4):901-911. doi: 10.1158/0008-5472.CAN-19-1794. Epub 2019 Dec 19. Cancer Res. 2020. PMID: 31857292 Free PMC article.

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