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Re-engineering aryl methylcarbamates to confer high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase.
Hartsel JA, Wong DM, Mutunga JM, Ma M, Anderson TD, Wysinski A, Islam R, Wong EA, Paulson SL, Li J, Lam PC, Totrov MM, Bloomquist JR, Carlier PR. Hartsel JA, et al. Among authors: carlier pr. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4593-8. doi: 10.1016/j.bmcl.2012.05.103. Epub 2012 Jun 6. Bioorg Med Chem Lett. 2012. PMID: 22738634 Free PMC article.
Aryl methylcarbamates: potency and selectivity towards wild-type and carbamate-insensitive (G119S) Anopheles gambiae acetylcholinesterase, and toxicity to G3 strain An. gambiae.
Wong DM, Li J, Lam PC, Hartsel JA, Mutunga JM, Totrov M, Bloomquist JR, Carlier PR. Wong DM, et al. Among authors: carlier pr. Chem Biol Interact. 2013 Mar 25;203(1):314-8. doi: 10.1016/j.cbi.2012.09.001. Epub 2012 Sep 16. Chem Biol Interact. 2013. PMID: 22989775 Free PMC article.
Select small core structure carbamates exhibit high contact toxicity to "carbamate-resistant" strain malaria mosquitoes, Anopheles gambiae (Akron).
Wong DM, Li J, Chen QH, Han Q, Mutunga JM, Wysinski A, Anderson TD, Ding H, Carpenetti TL, Verma A, Islam R, Paulson SL, Lam PC, Totrov M, Bloomquist JR, Carlier PR. Wong DM, et al. Among authors: carlier pr. PLoS One. 2012;7(10):e46712. doi: 10.1371/journal.pone.0046712. Epub 2012 Oct 1. PLoS One. 2012. PMID: 23049714 Free PMC article.
Inhibitor profile of bis(n)-tacrines and N-methylcarbamates on acetylcholinesterase from Rhipicephalus (Boophilus) microplus and Phlebotomus papatasi.
Swale DR, Tong F, Temeyer KB, Li A, Lam PC, Totrov MM, Carlier PR, Pérez de León AA, Bloomquist JR. Swale DR, et al. Among authors: carlier pr. Pestic Biochem Physiol. 2013 Jul 1;106(3):10.1016/j.pestbp.2013.03.005. doi: 10.1016/j.pestbp.2013.03.005. Pestic Biochem Physiol. 2013. PMID: 24187393 Free PMC article.
99 results