Ayan-Oshodi M - Search Results

1

Development Review of the BACE1 Inhibitor Lanabecestat (AZD3293/LY3314814).

Sims JR, Selzler KJ, Downing AM, Willis BA, Aluise CD, Zimmer J, Bragg S, Andersen S, Ayan-Oshodi M, Liffick E, Eads J, Wessels AM, Monk S, Schumi J, Mullen J. Sims JR, et al. Among authors: ayan oshodi m. J Prev Alzheimers Dis. 2017;4(4):247-254. doi: 10.14283/jpad.2017.38. J Prev Alzheimers Dis. 2017. PMID: 29181490 Review.

2

Assessment of Transporter Polymorphisms as a Factor in a BCRP Drug Interaction Study With Lanabecestat.

Willis BA, Andersen SW, Ayan-Oshodi M, James DE, Liffick E, Hillgren K, Guo Y, Monk SA. Willis BA, et al. Among authors: ayan oshodi m. J Clin Pharmacol. 2020 Jan;60(1):107-116. doi: 10.1002/jcph.1500. Epub 2019 Aug 5. J Clin Pharmacol. 2020. PMID: 31378968 Clinical Trial.

3

Clinically Negligible Pharmacokinetic and Pharmacodynamic Interactions Between Lanabecestat and Dabigatran Etexilate, a Prototypical P-gp Substrate.

Monk SA, Kugler AR, Andersen SW, Ayan-Oshodi MA, James DE, Mullen J, Zimmer JA, Willis BA. Monk SA, et al. Among authors: ayan oshodi ma. J Clin Pharmacol. 2020 May;60(5):586-594. doi: 10.1002/jcph.1558. Epub 2019 Dec 18. J Clin Pharmacol. 2020. PMID: 31853995

4

Pharmacokinetics and Pharmacodynamics of LY2599666, a PEG-Linked Antigen Binding Fragment that Targets Soluble Monomer Amyloid-β.

Li L, Zhen EY, Decker RL, Willis BA, Waters D, Liu P, Hake AM, Demattos RB, Ayan-Oshodi M. Li L, et al. Among authors: ayan oshodi m. J Alzheimers Dis. 2019;68(1):137-144. doi: 10.3233/JAD-180925. J Alzheimers Dis. 2019. PMID: 30741684 Clinical Trial.

5

QT effect of semagacestat at therapeutic and supratherapeutic doses.

Zhang W, Ayan-Oshodi M, Willis BA, Annes W, Hall SD, Chiesa J, Seger M. Zhang W, et al. Among authors: ayan oshodi m. Int J Clin Pharmacol Ther. 2012 Apr;50(4):290-9. doi: 10.5414/cp201672. Int J Clin Pharmacol Ther. 2012. PMID: 22456300 Clinical Trial.

6

Semagacestat pharmacokinetics are not significantly affected by formulation, food, or time of dosing in healthy participants.

Willis BA, Zhang W, Ayan-Oshodi M, Lowe SL, Annes WF, Sirois PJ, Friedrich S, de la Peña A. Willis BA, et al. J Clin Pharmacol. 2012 Jun;52(6):904-13. doi: 10.1177/0091270011407195. Epub 2011 Jul 1. J Clin Pharmacol. 2012. PMID: 21724950 Clinical Trial.

7

The effects on metabolic clearance when administering a potent CYP3A autoinducer with the prototypic CYP3A inhibitor, ketoconazole.

Ayan-Oshodi MA, Willis BA, Annes WF, Lowe SL, Friedrich S, de la Peña A, Zhang W, Brown T, Wise SD, Hall SD. Ayan-Oshodi MA, et al. Drug Metab Dispos. 2012 Oct;40(10):1945-52. doi: 10.1124/dmd.112.046060. Epub 2012 Jul 12. Drug Metab Dispos. 2012. PMID: 22789530 Clinical Trial.

8

Disposition and metabolism of semagacestat, a {gamma}-secretase inhibitor, in humans.

Yi P, Hadden C, Kulanthaivel P, Calvert N, Annes W, Brown T, Barbuch RJ, Chaudhary A, Ayan-Oshodi MA, Ring BJ. Yi P, et al. Drug Metab Dispos. 2010 Apr;38(4):554-65. doi: 10.1124/dmd.109.030841. Epub 2010 Jan 14. Drug Metab Dispos. 2010. PMID: 20075192

9

Adverse events in healthy subjects exposed to single and multiple doses of LY2140023 monohydrate: pooled results from 10 phase 1 studies.

Ayan-Oshodi M, Wondmagegnehu ET, Lowe SL, Kryzhanovskaya L, Walker DJ, Kinon BJ. Ayan-Oshodi M, et al. J Clin Psychopharmacol. 2012 Jun;32(3):408-11. doi: 10.1097/JCP.0b013e3182542633. J Clin Psychopharmacol. 2012. PMID: 22544017

10

In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1.

Pak YA, Long AJ, Annes WF, Witcher JW, Knadler MP, Ayan-Oshodi MA, Mitchell MI, Leese P, Hillgren KM. Pak YA, et al. Among authors: ayan oshodi ma. Drug Metab Dispos. 2017 Feb;45(2):137-144. doi: 10.1124/dmd.116.071118. Epub 2016 Nov 28. Drug Metab Dispos. 2017. PMID: 27895114 Free PMC article.

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