Holtzman DM - Search Results

1

Preclinical and Clinical Development of ABBV-8E12, a Humanized Anti-Tau Antibody, for Treatment of Alzheimer's Disease and Other Tauopathies.

West T, Hu Y, Verghese PB, Bateman RJ, Braunstein JB, Fogelman I, Budur K, Florian H, Mendonca N, Holtzman DM. West T, et al. Among authors: holtzman dm. J Prev Alzheimers Dis. 2017;4(4):236-241. doi: 10.14283/jpad.2017.36. J Prev Alzheimers Dis. 2017. PMID: 29181488 Clinical Trial.

2

Role of caspase-3 in ethanol-induced developmental neurodegeneration.

Young C, Roth KA, Klocke BJ, West T, Holtzman DM, Labruyere J, Qin YQ, Dikranian K, Olney JW. Young C, et al. Among authors: holtzman dm. Neurobiol Dis. 2005 Nov;20(2):608-14. doi: 10.1016/j.nbd.2005.04.014. Epub 2005 May 31. Neurobiol Dis. 2005. PMID: 15927478

3

Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid.

Hu Y, Malone JP, Fagan AM, Townsend RR, Holtzman DM. Hu Y, et al. Among authors: holtzman dm. Mol Cell Proteomics. 2005 Dec;4(12):2000-9. doi: 10.1074/mcp.M500207-MCP200. Epub 2005 Sep 30. Mol Cell Proteomics. 2005. PMID: 16199891 Free article.

4

Caspase-3 deficiency during development increases vulnerability to hypoxic-ischemic injury through caspase-3-independent pathways.

West T, Atzeva M, Holtzman DM. West T, et al. Among authors: holtzman dm. Neurobiol Dis. 2006 Jun;22(3):523-37. doi: 10.1016/j.nbd.2005.12.017. Epub 2006 Feb 9. Neurobiol Dis. 2006. PMID: 16480886

5

Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo.

Bateman RJ, Munsell LY, Morris JC, Swarm R, Yarasheski KE, Holtzman DM. Bateman RJ, et al. Among authors: holtzman dm. Nat Med. 2006 Jul;12(7):856-61. doi: 10.1038/nm1438. Epub 2006 Jun 25. Nat Med. 2006. PMID: 16799555 Free PMC article.

6

Fluctuations of CSF amyloid-beta levels: implications for a diagnostic and therapeutic biomarker.

Bateman RJ, Wen G, Morris JC, Holtzman DM. Bateman RJ, et al. Among authors: holtzman dm. Neurology. 2007 Feb 27;68(9):666-9. doi: 10.1212/01.wnl.0000256043.50901.e3. Neurology. 2007. PMID: 17325273

7

Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates.

Bateman RJ, Munsell LY, Chen X, Holtzman DM, Yarasheski KE. Bateman RJ, et al. Among authors: holtzman dm. J Am Soc Mass Spectrom. 2007 Jun;18(6):997-1006. doi: 10.1016/j.jasms.2007.02.009. Epub 2007 Feb 22. J Am Soc Mass Spectrom. 2007. PMID: 17383190 Free PMC article.

8

Pomegranate polyphenols and resveratrol protect the neonatal brain against hypoxic-ischemic injury.

West T, Atzeva M, Holtzman DM. West T, et al. Among authors: holtzman dm. Dev Neurosci. 2007;29(4-5):363-72. doi: 10.1159/000105477. Dev Neurosci. 2007. PMID: 17762204 Free PMC article.

9

Biomarkers of Alzheimer's disease.

Craig-Schapiro R, Fagan AM, Holtzman DM. Craig-Schapiro R, et al. Among authors: holtzman dm. Neurobiol Dis. 2009 Aug;35(2):128-40. doi: 10.1016/j.nbd.2008.10.003. Epub 2008 Oct 28. Neurobiol Dis. 2009. PMID: 19010417 Free PMC article. Review.

10

A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system.

Bateman RJ, Siemers ER, Mawuenyega KG, Wen G, Browning KR, Sigurdson WC, Yarasheski KE, Friedrich SW, Demattos RB, May PC, Paul SM, Holtzman DM. Bateman RJ, et al. Among authors: holtzman dm. Ann Neurol. 2009 Jul;66(1):48-54. doi: 10.1002/ana.21623. Ann Neurol. 2009. PMID: 19360898 Free PMC article. Clinical Trial.

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