Light PE - Search Results

1

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis.

Ondrusova K, Fatehi M, Barr A, Czarnecka Z, Long W, Suzuki K, Campbell S, Philippaert K, Hubert M, Tredget E, Kwan P, Touret N, Wabitsch M, Lee KY, Light PE. Ondrusova K, et al. Among authors: light pe. Sci Rep. 2017 Nov 27;7(1):16332. doi: 10.1038/s41598-017-16689-4. Sci Rep. 2017. PMID: 29180820 Free PMC article.

2

The ATP-sensitive K(+) channel ABCC8 S1369A type 2 diabetes risk variant increases MgATPase activity.

Fatehi M, Raja M, Carter C, Soliman D, Holt A, Light PE. Fatehi M, et al. Among authors: light pe. Diabetes. 2012 Jan;61(1):241-9. doi: 10.2337/db11-0371. Diabetes. 2012. PMID: 22187380 Free PMC article.

3

Pharmacogenomic analysis of ATP-sensitive potassium channels coexpressing the common type 2 diabetes risk variants E23K and S1369A.

Lang VY, Fatehi M, Light PE. Lang VY, et al. Among authors: light pe. Pharmacogenet Genomics. 2012 Mar;22(3):206-14. doi: 10.1097/FPC.0b013e32835001e7. Pharmacogenet Genomics. 2012. PMID: 22209866

4

Late sodium current inhibition alone with ranolazine is sufficient to reduce ischemia- and cardiac glycoside-induced calcium overload and contractile dysfunction mediated by reverse-mode sodium/calcium exchange.

Soliman D, Wang L, Hamming KS, Yang W, Fatehi M, Carter CC, Clanachan AS, Light PE. Soliman D, et al. Among authors: light pe. J Pharmacol Exp Ther. 2012 Nov;343(2):325-32. doi: 10.1124/jpet.112.196949. Epub 2012 Aug 9. J Pharmacol Exp Ther. 2012. PMID: 22879384

5

Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity.

Fatehi M, Carter CR, Youssef N, Hunter BE, Holt A, Light PE. Fatehi M, et al. Among authors: light pe. Biosci Rep. 2015 Jul 7;35(4):e00238. doi: 10.1042/BSR20150143. Biosci Rep. 2015. PMID: 26181369 Free PMC article.

6

The mechano-sensitivity of cardiac ATP-sensitive potassium channels is mediated by intrinsic MgATPase activity.

Fatehi M, Carter CC, Youssef N, Light PE. Fatehi M, et al. Among authors: light pe. J Mol Cell Cardiol. 2017 Jul;108:34-41. doi: 10.1016/j.yjmcc.2017.05.004. Epub 2017 May 5. J Mol Cell Cardiol. 2017. PMID: 28483598

7

Hearts lacking plasma membrane K_ATP channels display changes in basal aerobic metabolic substrate preference and AMPK activity.

Youssef N, Campbell S, Barr A, Gandhi M, Hunter B, Dolinsky V, Dyck JRB, Clanachan AS, Light PE. Youssef N, et al. Among authors: light pe. Am J Physiol Heart Circ Physiol. 2017 Sep 1;313(3):H469-H478. doi: 10.1152/ajpheart.00612.2016. Epub 2017 Jun 30. Am J Physiol Heart Circ Physiol. 2017. PMID: 28667052 Free article.

8

Identification and characterization of hydrophobic gate residues in TRP channels.

Zheng W, Hu R, Cai R, Hofmann L, Hu Q, Fatehi M, Long W, Kong T, Tang J, Light P, Flockerzi V, Cao Y, Chen XZ. Zheng W, et al. FASEB J. 2018 Feb;32(2):639-653. doi: 10.1096/fj.201700599RR. Epub 2018 Jan 4. FASEB J. 2018. PMID: 28970257

9

Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2.

Zheng W, Cai R, Hofmann L, Nesin V, Hu Q, Long W, Fatehi M, Liu X, Hussein S, Kong T, Li J, Light PE, Tang J, Flockerzi V, Tsiokas L, Chen XZ. Zheng W, et al. Among authors: light pe. Cell Rep. 2018 Feb 6;22(6):1560-1573. doi: 10.1016/j.celrep.2018.01.042. Cell Rep. 2018. PMID: 29425510 Free PMC article.

10

Costarting sitagliptin with metformin is associated with a lower likelihood of disease progression in newly treated people with type 2 diabetes: a cohort study.

Campbell SA, Light PE, Simpson SH. Campbell SA, et al. Among authors: light pe. Diabet Med. 2020 Oct;37(10):1715-1722. doi: 10.1111/dme.14154. Epub 2019 Nov 6. Diabet Med. 2020. PMID: 31618475

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