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Chemoproteomics Identifies State-Dependent and Proteoform-Selective Caspase-2 Inhibitors.
Castellón JO, Ofori S, Burton NR, Julio AR, Turmon AC, Armenta E, Sandoval C, Boatner LM, Takayoshi EE, Faragalla M, Taylor C, Zhou AL, Tran K, Shek J, Yan T, Desai HS, Fregoso OI, Damoiseaux R, Backus KM. Castellón JO, et al. Among authors: backus km. J Am Chem Soc. 2024 Jun 5;146(22):14972-14988. doi: 10.1021/jacs.3c12240. Epub 2024 May 24. J Am Chem Soc. 2024. PMID: 38787738
Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome.
Yan T, Julio AR, Villanueva M, Jones AE, Ball AB, Boatner LM, Turmon AC, Yen SL, Desai HS, Divakaruni AS, Backus KM. Yan T, et al. Among authors: backus km. bioRxiv [Preprint]. 2023 Jan 31:2023.01.22.525042. doi: 10.1101/2023.01.22.525042. bioRxiv. 2023. Update in: Cell Chem Biol. 2023 Jul 20;30(7):811-827.e7. doi: 10.1016/j.chembiol.2023.06.008 PMID: 36711448 Free PMC article. Updated. Preprint.
Chemoproteomics identifies proteoform-selective caspase-2 inhibitors.
Castellón JO, Ofori S, Armenta E, Burton N, Boatner LM, Takayoshi EE, Faragalla M, Zhou A, Tran K, Shek J, Yan T, Desai HS, Backus KM. Castellón JO, et al. Among authors: backus km. bioRxiv [Preprint]. 2023 Oct 26:2023.10.25.563785. doi: 10.1101/2023.10.25.563785. bioRxiv. 2023. Update in: J Am Chem Soc. 2024 Jun 5;146(22):14972-14988. doi: 10.1021/jacs.3c12240 PMID: 37961563 Free PMC article. Updated. Preprint.
Proteome-wide covalent ligand discovery in native biological systems.
Backus KM, Correia BE, Lum KM, Forli S, Horning BD, González-Páez GE, Chatterjee S, Lanning BR, Teijaro JR, Olson AJ, Wolan DW, Cravatt BF. Backus KM, et al. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15. Nature. 2016. PMID: 27309814 Free PMC article.
46 results