Duffy MR - Search Results

1

Generation and characterization of a novel candidate gene therapy and vaccination vector based on human species D adenovirus type 56.

Duffy MR, Alonso-Padilla J, John L, Chandra N, Khan S, Ballmann MZ, Lipiec A, Heemskerk E, Custers J, Arnberg N, Havenga M, Baker AH, Lemckert A. Duffy MR, et al. J Gen Virol. 2018 Jan;99(1):135-147. doi: 10.1099/jgv.0.000978. Epub 2017 Nov 20. J Gen Virol. 2018. PMID: 29154744 Free article.

2

Retargeting FX-binding-ablated HAdV-5 to vascular cells by inclusion of the RGD-4C peptide in hexon hypervariable region 7 and the HI loop.

Robertson S, Parker AL, Clarke C, Duffy MR, Alba R, Nicklin SA, Baker AH. Robertson S, et al. Among authors: duffy mr. J Gen Virol. 2016 Aug;97(8):1911-1916. doi: 10.1099/jgv.0.000505. Epub 2016 May 16. J Gen Virol. 2016. PMID: 27189759 Free PMC article.

3

Defining a Novel Role for the Coxsackievirus and Adenovirus Receptor in Human Adenovirus Serotype 5 Transduction In Vitro in the Presence of Mouse Serum.

Lopez-Gordo E, Doszpoly A, Duffy MR, Coughlan L, Bradshaw AC, White KM, Denby L, Nicklin SA, Baker AH. Lopez-Gordo E, et al. Among authors: duffy mr. J Virol. 2017 May 26;91(12):e02487-16. doi: 10.1128/JVI.02487-16. Print 2017 Jun 15. J Virol. 2017. PMID: 28381574 Free PMC article.

4

The relevance of coagulation factor X protection of adenoviruses in human sera.

Duffy MR, Doszpoly A, Turner G, Nicklin SA, Baker AH. Duffy MR, et al. Gene Ther. 2016 Jul;23(7):592-6. doi: 10.1038/gt.2016.32. Epub 2016 Mar 25. Gene Ther. 2016. PMID: 27014840 Free PMC article.

5

A cluster of basic amino acids in the factor X serine protease mediates surface attachment of adenovirus/FX complexes.

Duffy MR, Bradshaw AC, Parker AL, McVey JH, Baker AH. Duffy MR, et al. J Virol. 2011 Oct;85(20):10914-9. doi: 10.1128/JVI.05382-11. Epub 2011 Aug 17. J Virol. 2011. PMID: 21849463 Free PMC article.

6

Manipulation of adenovirus interactions with host factors for gene therapy applications.

Duffy MR, Parker AL, Bradshaw AC, Baker AH. Duffy MR, et al. Nanomedicine (Lond). 2012 Feb;7(2):271-88. doi: 10.2217/nnm.11.186. Nanomedicine (Lond). 2012. PMID: 22339136 Review.

7

Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo.

Ma J, Duffy MR, Deng L, Dakin RS, Uil T, Custers J, Kelly SM, McVey JH, Nicklin SA, Baker AH. Ma J, et al. Among authors: duffy mr. PLoS Pathog. 2015 Feb 6;11(2):e1004673. doi: 10.1371/journal.ppat.1004673. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25658827 Free PMC article.

8

Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach.

Duffy MR, Parker AL, Kalkman ER, White K, Kovalskyy D, Kelly SM, Baker AH. Duffy MR, et al. J Control Release. 2013 Aug 28;170(1):132-40. doi: 10.1016/j.jconrel.2013.05.007. Epub 2013 May 20. J Control Release. 2013. PMID: 23702233 Free article.

9

Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X.

Bradshaw AC, Parker AL, Duffy MR, Coughlan L, van Rooijen N, Kähäri VM, Nicklin SA, Baker AH. Bradshaw AC, et al. Among authors: duffy mr. PLoS Pathog. 2010 Oct 7;6(10):e1001142. doi: 10.1371/journal.ppat.1001142. PLoS Pathog. 2010. PMID: 20949078 Free PMC article.

10

Self-attenuating adenovirus enables production of recombinant adeno-associated virus for high manufacturing yield without contamination.

Su W, Patrício MI, Duffy MR, Krakowiak JM, Seymour LW, Cawood R. Su W, et al. Among authors: duffy mr. Nat Commun. 2022 Mar 7;13(1):1182. doi: 10.1038/s41467-022-28738-2. Nat Commun. 2022. PMID: 35256603 Free PMC article.

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