Alessi DR - Search Results

1

Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase.

Lis P, Burel S, Steger M, Mann M, Brown F, Diez F, Tonelli F, Holton JL, Ho PW, Ho SL, Chou MY, Polinski NK, Martinez TN, Davies P, Alessi DR. Lis P, et al. Among authors: alessi dr. Biochem J. 2018 Jan 2;475(1):1-22. doi: 10.1042/BCJ20170802. Biochem J. 2018. PMID: 29127256 Free PMC article.

2

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf.

Cross DA, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, Cohen P. Cross DA, et al. Among authors: alessi dr. Biochem J. 1994 Oct 1;303 ( Pt 1)(Pt 1):21-6. doi: 10.1042/bj3030021. Biochem J. 1994. PMID: 7945242 Free PMC article.

3

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation.

James SR, Downes CP, Gigg R, Grove SJ, Holmes AB, Alessi DR. James SR, et al. Among authors: alessi dr. Biochem J. 1996 May 1;315 ( Pt 3)(Pt 3):709-13. doi: 10.1042/bj3150709. Biochem J. 1996. PMID: 8645147 Free PMC article.

4

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR. Walker KS, et al. Among authors: alessi dr. Biochem J. 1998 Apr 1;331 ( Pt 1)(Pt 1):299-308. doi: 10.1042/bj3310299. Biochem J. 1998. PMID: 9512493 Free PMC article.

5

The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2.

Shaw M, Cohen P, Alessi DR. Shaw M, et al. Among authors: alessi dr. Biochem J. 1998 Nov 15;336 ( Pt 1)(Pt 1):241-6. doi: 10.1042/bj3360241. Biochem J. 1998. PMID: 9806907 Free PMC article.

6

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.

Currie RA, Walker KS, Gray A, Deak M, Casamayor A, Downes CP, Cohen P, Alessi DR, Lucocq J. Currie RA, et al. Among authors: alessi dr. Biochem J. 1999 Feb 1;337 ( Pt 3)(Pt 3):575-83. Biochem J. 1999. PMID: 9895304 Free PMC article.

7

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo.

Casamayor A, Morrice NA, Alessi DR. Casamayor A, et al. Among authors: alessi dr. Biochem J. 1999 Sep 1;342 ( Pt 2)(Pt 2):287-92. Biochem J. 1999. PMID: 10455013 Free PMC article.

8

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

Navé BT, Ouwens M, Withers DJ, Alessi DR, Shepherd PR. Navé BT, et al. Among authors: alessi dr. Biochem J. 1999 Dec 1;344 Pt 2(Pt 2):427-31. Biochem J. 1999. PMID: 10567225 Free PMC article.

9

Phosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinase.

Dowler S, Montalvo L, Cantrell D, Morrice N, Alessi DR. Dowler S, et al. Among authors: alessi dr. Biochem J. 2000 Jul 15;349(Pt 2):605-10. doi: 10.1042/0264-6021:3490605. Biochem J. 2000. PMID: 10880360 Free PMC article.

10

Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR. Dowler S, et al. Among authors: alessi dr. Biochem J. 2000 Oct 1;351(Pt 1):19-31. doi: 10.1042/0264-6021:3510019. Biochem J. 2000. PMID: 11001876 Free PMC article.

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