Alessi DR - Search Results

1

Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.

Fan Y, Howden AJM, Sarhan AR, Lis P, Ito G, Martinez TN, Brockmann K, Gasser T, Alessi DR, Sammler EM. Fan Y, et al. Among authors: alessi dr. Biochem J. 2018 Jan 2;475(1):23-44. doi: 10.1042/BCJ20170803. Biochem J. 2018. PMID: 29127255 Free PMC article.

2

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf.

Cross DA, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, Cohen P. Cross DA, et al. Among authors: alessi dr. Biochem J. 1994 Oct 1;303 ( Pt 1)(Pt 1):21-6. doi: 10.1042/bj3030021. Biochem J. 1994. PMID: 7945242 Free PMC article.

3

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR. Walker KS, et al. Among authors: alessi dr. Biochem J. 1998 Apr 1;331 ( Pt 1)(Pt 1):299-308. doi: 10.1042/bj3310299. Biochem J. 1998. PMID: 9512493 Free PMC article.

4

The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2.

Shaw M, Cohen P, Alessi DR. Shaw M, et al. Among authors: alessi dr. Biochem J. 1998 Nov 15;336 ( Pt 1)(Pt 1):241-6. doi: 10.1042/bj3360241. Biochem J. 1998. PMID: 9806907 Free PMC article.

5

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.

Currie RA, Walker KS, Gray A, Deak M, Casamayor A, Downes CP, Cohen P, Alessi DR, Lucocq J. Currie RA, et al. Among authors: alessi dr. Biochem J. 1999 Feb 1;337 ( Pt 3)(Pt 3):575-83. Biochem J. 1999. PMID: 9895304 Free PMC article.

6

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo.

Casamayor A, Morrice NA, Alessi DR. Casamayor A, et al. Among authors: alessi dr. Biochem J. 1999 Sep 1;342 ( Pt 2)(Pt 2):287-92. Biochem J. 1999. PMID: 10455013 Free PMC article.

7

Phosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinase.

Dowler S, Montalvo L, Cantrell D, Morrice N, Alessi DR. Dowler S, et al. Among authors: alessi dr. Biochem J. 2000 Jul 15;349(Pt 2):605-10. doi: 10.1042/0264-6021:3490605. Biochem J. 2000. PMID: 10880360 Free PMC article.

8

Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lecture.

Alessi DR. Alessi DR. Biochem Soc Trans. 2001 May;29(Pt 2):1-14. doi: 10.1042/0300-5127:0290001. Biochem Soc Trans. 2001. PMID: 11356119

9

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.

Sapkota GP, Boudeau J, Deak M, Kieloch A, Morrice N, Alessi DR. Sapkota GP, et al. Among authors: alessi dr. Biochem J. 2002 Mar 1;362(Pt 2):481-90. doi: 10.1042/0264-6021:3620481. Biochem J. 2002. PMID: 11853558 Free PMC article.

10

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.

Douglas P, Sapkota GP, Morrice N, Yu Y, Goodarzi AA, Merkle D, Meek K, Alessi DR, Lees-Miller SP. Douglas P, et al. Among authors: alessi dr. Biochem J. 2002 Nov 15;368(Pt 1):243-51. doi: 10.1042/BJ20020973. Biochem J. 2002. PMID: 12186630 Free PMC article.

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