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Granulocyte colony-stimulating factor and autologous CD133-positive stem-cell therapy in liver cirrhosis (REALISTIC): an open-label, randomised, controlled phase 2 trial.
Newsome PN, Fox R, King AL, Barton D, Than NN, Moore J, Corbett C, Townsend S, Thomas J, Guo K, Hull D, Beard HA, Thompson J, Atkinson A, Bienek C, McGowan N, Guha N, Campbell J, Hollyman D, Stocken D, Yap C, Forbes SJ. Newsome PN, et al. Among authors: moore j. Lancet Gastroenterol Hepatol. 2018 Jan;3(1):25-36. doi: 10.1016/S2468-1253(17)30326-6. Epub 2017 Nov 7. Lancet Gastroenterol Hepatol. 2018. PMID: 29127060 Free PMC article. Clinical Trial.
Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis.
Fraser AR, Pass C, Burgoyne P, Atkinson A, Bailey L, Laurie A, W A McGowan N, Hamid A, Moore JK, Dwyer BJ, Turner ML, Forbes SJ, Campbell JDM. Fraser AR, et al. Among authors: moore jk. Cytotherapy. 2017 Sep;19(9):1113-1124. doi: 10.1016/j.jcyt.2017.05.009. Epub 2017 Jun 30. Cytotherapy. 2017. PMID: 28673774 Free PMC article.
Safety profile of autologous macrophage therapy for liver cirrhosis.
Moroni F, Dwyer BJ, Graham C, Pass C, Bailey L, Ritchie L, Mitchell D, Glover A, Laurie A, Doig S, Hargreaves E, Fraser AR, Turner ML, Campbell JDM, McGowan NWA, Barry J, Moore JK, Hayes PC, Leeming DJ, Nielsen MJ, Musa K, Fallowfield JA, Forbes SJ. Moroni F, et al. Among authors: moore jk. Nat Med. 2019 Oct;25(10):1560-1565. doi: 10.1038/s41591-019-0599-8. Epub 2019 Oct 7. Nat Med. 2019. PMID: 31591593 Clinical Trial.
Trientine tetrahydrochloride versus penicillamine for maintenance therapy in Wilson disease (CHELATE): a randomised, open-label, non-inferiority, phase 3 trial.
Schilsky ML, Czlonkowska A, Zuin M, Cassiman D, Twardowschy C, Poujois A, Gondim FAA, Denk G, Cury RG, Ott P, Moore J, Ala A, D'Inca R, Couchonnal-Bedoya E, D'Hollander K, Dubois N, Kamlin COF, Weiss KH; CHELATE trial investigators. Schilsky ML, et al. Among authors: moore j. Lancet Gastroenterol Hepatol. 2022 Dec;7(12):1092-1102. doi: 10.1016/S2468-1253(22)00270-9. Epub 2022 Sep 30. Lancet Gastroenterol Hepatol. 2022. PMID: 36183738 Clinical Trial.
Macrophage Therapy for Acute Liver Injury (MAIL): a study protocol for a phase 1 randomised, open-label, dose-escalation study to evaluate safety, tolerability and activity of allogeneic alternatively activated macrophages in patients with paracetamol-induced acute liver injury in the UK.
Humphries C, Addison M, Aithal G, Boyd J, Briody L, Campbell JDM, Candela ME, Clarke E, Coulson J, Downing-James N, Fontana RJ, Geddes A, Grahamslaw J, Grant A, Heye A, Hutchinson JA, Jones A, Mitchell F, Moore J, Riddell A, Rodriguez A, Thomas A, Tucker G, Walker K, Weir CJ, Woods R, Zahra S, Forbes SJ, Dear JW. Humphries C, et al. Among authors: moore j. BMJ Open. 2024 Dec 9;14(12):e089417. doi: 10.1136/bmjopen-2024-089417. BMJ Open. 2024. PMID: 39653576 Free PMC article.
Acute kidney injury in acute liver failure: a review.
Moore JK, Love E, Craig DG, Hayes PC, Simpson KJ. Moore JK, et al. Expert Rev Gastroenterol Hepatol. 2013 Nov;7(8):701-12. doi: 10.1586/17474124.2013.837264. Epub 2013 Oct 17. Expert Rev Gastroenterol Hepatol. 2013. PMID: 24134153 Review.
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