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Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease.
Chan EY, Luthi-Carter R, Strand A, Solano SM, Hanson SA, DeJohn MM, Kooperberg C, Chase KO, DiFiglia M, Young AB, Leavitt BR, Cha JH, Aronin N, Hayden MR, Olson JM. Chan EY, et al. Among authors: hayden mr. Hum Mol Genet. 2002 Aug 15;11(17):1939-51. doi: 10.1093/hmg/11.17.1939. Hum Mol Genet. 2002. PMID: 12165556
HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis.
Singaraja RR, Hadano S, Metzler M, Givan S, Wellington CL, Warby S, Yanai A, Gutekunst CA, Leavitt BR, Yi H, Fichter K, Gan L, McCutcheon K, Chopra V, Michel J, Hersch SM, Ikeda JE, Hayden MR. Singaraja RR, et al. Among authors: hayden mr. Hum Mol Genet. 2002 Nov 1;11(23):2815-28. doi: 10.1093/hmg/11.23.2815. Hum Mol Genet. 2002. PMID: 12393793
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Slow EJ, van Raamsdonk J, Rogers D, Coleman SH, Graham RK, Deng Y, Oh R, Bissada N, Hossain SM, Yang YZ, Li XJ, Simpson EM, Gutekunst CA, Leavitt BR, Hayden MR. Slow EJ, et al. Among authors: hayden mr. Hum Mol Genet. 2003 Jul 1;12(13):1555-67. doi: 10.1093/hmg/ddg169. Hum Mol Genet. 2003. PMID: 12812983
900 results