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High throughput ADME screening: practical considerations, impact on the portfolio and enabler of in silico ADME models.
Hop CE, Cole MJ, Davidson RE, Duignan DB, Federico J, Janiszewski JS, Jenkins K, Krueger S, Lebowitz R, Liston TE, Mitchell W, Snyder M, Steyn SJ, Soglia JR, Taylor C, Troutman MD, Umland J, West M, Whalen KM, Zelesky V, Zhao SX. Hop CE, et al. Among authors: janiszewski js. Curr Drug Metab. 2008 Nov;9(9):847-53. doi: 10.2174/138920008786485092. Curr Drug Metab. 2008. PMID: 18991580 Review.
Discovery of Compounds that Positively Modulate the High Affinity Choline Transporter.
Choudhary P, Armstrong EJ, Jorgensen CC, Piotrowski M, Barthmes M, Torella R, Johnston SE, Maruyama Y, Janiszewski JS, Storer RI, Skerratt SE, Benn CL. Choudhary P, et al. Among authors: janiszewski js. Front Mol Neurosci. 2017 Feb 27;10:40. doi: 10.3389/fnmol.2017.00040. eCollection 2017. Front Mol Neurosci. 2017. PMID: 28289374 Free PMC article.
Assessing Physicochemical Properties of Drug Molecules via Microsolvation Measurements with Differential Mobility Spectrometry.
Liu C, Le Blanc JC, Schneider BB, Shields J, Federico JJ 3rd, Zhang H, Stroh JG, Kauffman GW, Kung DW, Ieritano C, Shepherdson E, Verbuyst M, Melo L, Hasan M, Naser D, Janiszewski JS, Hopkins WS, Campbell JL. Liu C, et al. Among authors: janiszewski js. ACS Cent Sci. 2017 Feb 22;3(2):101-109. doi: 10.1021/acscentsci.6b00297. Epub 2017 Feb 10. ACS Cent Sci. 2017. PMID: 28280776 Free PMC article.
64 results