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Structure-based drug design: aiming for a perfect fit.
van Montfort RLM, Workman P. van Montfort RLM, et al. Among authors: workman p. Essays Biochem. 2017 Nov 8;61(5):431-437. doi: 10.1042/EBC20170052. Print 2017 Nov 8. Essays Biochem. 2017. PMID: 29118091 Free PMC article. Review.
Structure-based design of molecular cancer therapeutics.
van Montfort RL, Workman P. van Montfort RL, et al. Among authors: workman p. Trends Biotechnol. 2009 May;27(5):315-28. doi: 10.1016/j.tibtech.2009.02.003. Epub 2009 Mar 30. Trends Biotechnol. 2009. PMID: 19339067 Review.
PI(3) kinases: revealing the delta lady.
Workman P, van Montfort RL. Workman P, et al. Nat Chem Biol. 2010 Feb;6(2):82-3. doi: 10.1038/nchembio.305. Nat Chem Biol. 2010. PMID: 20081818 No abstract available.
Objective assessment of cancer genes for drug discovery.
Patel MN, Halling-Brown MD, Tym JE, Workman P, Al-Lazikani B. Patel MN, et al. Among authors: workman p. Nat Rev Drug Discov. 2013 Jan;12(1):35-50. doi: 10.1038/nrd3913. Nat Rev Drug Discov. 2013. PMID: 23274470 Review.
The discovery of potent ribosomal S6 kinase inhibitors by high-throughput screening and structure-guided drug design.
Couty S, Westwood IM, Kalusa A, Cano C, Travers J, Boxall K, Chow CL, Burns S, Schmitt J, Pickard L, Barillari C, McAndrew PC, Clarke PA, Linardopoulos S, Griffin RJ, Aherne GW, Raynaud FI, Workman P, Jones K, van Montfort RL. Couty S, et al. Among authors: workman p. Oncotarget. 2013 Oct;4(10):1647-61. doi: 10.18632/oncotarget.1255. Oncotarget. 2013. PMID: 24072592 Free PMC article.
605 results