Huang TY - Search Results

1

SORLA attenuates EphA4 signaling and amyloid β-induced neurodegeneration.

Huang TY, Zhao Y, Jiang LL, Li X, Liu Y, Sun Y, Piña-Crespo JC, Zhu B, Masliah E, Willnow TE, Pasquale EB, Xu H. Huang TY, et al. J Exp Med. 2017 Dec 4;214(12):3669-3685. doi: 10.1084/jem.20171413. Epub 2017 Nov 7. J Exp Med. 2017. PMID: 29114064 Free PMC article.

2

A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation.

Huang TY, Michael S, Xu T, Sarkeshik A, Moresco JJ, Yates JR 3rd, Masliah E, Bokoch GM, DerMardirossian C. Huang TY, et al. Mol Biol Cell. 2013 Feb;24(3):194-209. doi: 10.1091/mbc.E12-07-0565. Epub 2012 Dec 5. Mol Biol Cell. 2013. PMID: 23223568 Free PMC article.

3

Dysregulation of protein trafficking in neurodegeneration.

Wang X, Huang T, Bu G, Xu H. Wang X, et al. Mol Neurodegener. 2014 Aug 25;9:31. doi: 10.1186/1750-1326-9-31. Mol Neurodegener. 2014. PMID: 25152012 Free PMC article. Review.

4

Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity.

Wang X, Huang T, Zhao Y, Zheng Q, Thompson RC, Bu G, Zhang YW, Hong W, Xu H. Wang X, et al. Cell Rep. 2014 Nov 6;9(3):1023-33. doi: 10.1016/j.celrep.2014.09.037. Epub 2014 Oct 23. Cell Rep. 2014. PMID: 25437557 Free PMC article.

5

Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis.

Zhao Y, Tseng IC, Heyser CJ, Rockenstein E, Mante M, Adame A, Zheng Q, Huang T, Wang X, Arslan PE, Chakrabarty P, Wu C, Bu G, Mobley WC, Zhang YW, St George-Hyslop P, Masliah E, Fraser P, Xu H. Zhao Y, et al. Neuron. 2015 Sep 2;87(5):963-75. doi: 10.1016/j.neuron.2015.08.020. Neuron. 2015. PMID: 26335643 Free PMC article.

6

RPS23RG1 reduces Aβ oligomer-induced synaptic and cognitive deficits.

Yan L, Chen Y, Li W, Huang X, Badie H, Jian F, Huang T, Zhao Y, Cohen SN, Li L, Zhang YW, Luo H, Tu S, Xu H. Yan L, et al. Sci Rep. 2016 Jan 6;6:18668. doi: 10.1038/srep18668. Sci Rep. 2016. PMID: 26733416 Free PMC article.

7

SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein.

Huang TY, Zhao Y, Li X, Wang X, Tseng IC, Thompson R, Tu S, Willnow TE, Zhang YW, Xu H. Huang TY, et al. J Neurosci. 2016 Jul 27;36(30):7996-8011. doi: 10.1523/JNEUROSCI.0206-16.2016. J Neurosci. 2016. PMID: 27466343 Free PMC article.

8

SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and Ciliogenesis.

Wang X, Zhou Y, Wang J, Tseng IC, Huang T, Zhao Y, Zheng Q, Gao Y, Luo H, Zhang X, Bu G, Hong W, Xu H. Wang X, et al. J Neurosci. 2016 Dec 14;36(50):12586-12597. doi: 10.1523/JNEUROSCI.1620-16.2016. J Neurosci. 2016. PMID: 27974614 Free PMC article.

9

Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases.

Zheng Q, Huang T, Zhang L, Zhou Y, Luo H, Xu H, Wang X. Zheng Q, et al. Front Aging Neurosci. 2016 Dec 15;8:303. doi: 10.3389/fnagi.2016.00303. eCollection 2016. Front Aging Neurosci. 2016. PMID: 28018215 Free PMC article. Review.

10

ER-associated degradation regulates Alzheimer's amyloid pathology and memory function by modulating γ-secretase activity.

Zhu B, Jiang L, Huang T, Zhao Y, Liu T, Zhong Y, Li X, Campos A, Pomeroy K, Masliah E, Zhang D, Xu H. Zhu B, et al. Nat Commun. 2017 Nov 13;8(1):1472. doi: 10.1038/s41467-017-01799-4. Nat Commun. 2017. PMID: 29133892 Free PMC article.

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