Loeb DM - Search Results

1

Inhibition of porcupine prolongs metastasis free survival in a mouse xenograft model of Ewing sarcoma.

Hayashi M, Baker A, Goldstein SD, Albert CM, Jackson KW, McCarty G, Kahlert UD, Loeb DM. Hayashi M, et al. Among authors: loeb dm. Oncotarget. 2017 Jul 21;8(45):78265-78276. doi: 10.18632/oncotarget.19432. eCollection 2017 Oct 3. Oncotarget. 2017. PMID: 29108227 Free PMC article.

2

Isoforms of Wilms' tumor suppressor gene (WT1) have distinct effects on mammary epithelial cells.

Burwell EA, McCarty GP, Simpson LA, Thompson KA, Loeb DM. Burwell EA, et al. Among authors: loeb dm. Oncogene. 2007 May 17;26(23):3423-30. doi: 10.1038/sj.onc.1210127. Epub 2006 Dec 11. Oncogene. 2007. PMID: 17160023

3

WT1 protein directly regulates expression of vascular endothelial growth factor and is a mediator of tumor response to hypoxia.

McCarty G, Awad O, Loeb DM. McCarty G, et al. Among authors: loeb dm. J Biol Chem. 2011 Dec 23;286(51):43634-43643. doi: 10.1074/jbc.M111.310128. Epub 2011 Oct 26. J Biol Chem. 2011. PMID: 22030397 Free PMC article.

4

A novel chordoma xenograft allows in vivo drug testing and reveals the importance of NF-κB signaling in chordoma biology.

Trucco MM, Awad O, Wilky BA, Goldstein SD, Huang R, Walker RL, Shah P, Katuri V, Gul N, Zhu YJ, McCarthy EF, Paz-Priel I, Meltzer PS, Austin CP, Xia M, Loeb DM. Trucco MM, et al. Among authors: loeb dm. PLoS One. 2013 Nov 6;8(11):e79950. doi: 10.1371/journal.pone.0079950. eCollection 2013. PLoS One. 2013. PMID: 24223206 Free PMC article.

5

WT1 regulates angiogenesis in Ewing Sarcoma.

Katuri V, Gerber S, Qiu X, McCarty G, Goldstein SD, Hammers H, Montgomery E, Chen AR, Loeb DM. Katuri V, et al. Among authors: loeb dm. Oncotarget. 2014 May 15;5(9):2436-49. doi: 10.18632/oncotarget.1610. Oncotarget. 2014. PMID: 24810959 Free PMC article.

6

Hypoxia-sensitive epigenetic regulation of an antisense-oriented lncRNA controls WT1 expression in myeloid leukemia cells.

McCarty G, Loeb DM. McCarty G, et al. Among authors: loeb dm. PLoS One. 2015 Mar 20;10(3):e0119837. doi: 10.1371/journal.pone.0119837. eCollection 2015. PLoS One. 2015. PMID: 25794157 Free PMC article.

7

IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas.

Huang X, Park H, Greene J, Pao J, Mulvey E, Zhou SX, Albert CM, Moy F, Sachdev D, Yee D, Rader C, Hamby CV, Loeb DM, Cairo MS, Zhou X. Huang X, et al. Among authors: loeb dm. PLoS One. 2015 Jul 14;10(7):e0133152. doi: 10.1371/journal.pone.0133152. eCollection 2015. PLoS One. 2015. PMID: 26173023 Free PMC article.

8

An orthotopic xenograft model with survival hindlimb amputation allows investigation of the effect of tumor microenvironment on sarcoma metastasis.

Goldstein SD, Hayashi M, Albert CM, Jackson KW, Loeb DM. Goldstein SD, et al. Among authors: loeb dm. Clin Exp Metastasis. 2015 Oct;32(7):703-15. doi: 10.1007/s10585-015-9738-x. Epub 2015 Aug 18. Clin Exp Metastasis. 2015. PMID: 26278104

9

Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcoma.

Kang Z, Goldstein SD, Yu Y, Meltzer PS, Loeb DM, Cao L. Kang Z, et al. Among authors: loeb dm. Br J Cancer. 2015 Sep 15;113(6):894-901. doi: 10.1038/bjc.2015.298. Epub 2015 Aug 20. Br J Cancer. 2015. PMID: 26291055 Free PMC article.

10

RNA helicase DDX3: a novel therapeutic target in Ewing sarcoma.

Wilky BA, Kim C, McCarty G, Montgomery EA, Kammers K, DeVine LR, Cole RN, Raman V, Loeb DM. Wilky BA, et al. Among authors: loeb dm. Oncogene. 2016 May 19;35(20):2574-83. doi: 10.1038/onc.2015.336. Epub 2015 Sep 14. Oncogene. 2016. PMID: 26364611

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